14 Result(s)
within
Hyun** Koo
Microbiology
-
Article
Open AccessAddition of cariogenic pathogens to complex oral microflora drives significant changes in biofilm compositions and functionalities
Dental caries is a microbe and sugar-mediated biofilm-dependent oral disease. Of particular significance, a virulent type of dental caries, known as severe early childhood caries (S-ECC), is characterized by t...
-
Article
Open AccessAmplification of LTRs of extrachromosomal linear DNAs (ALE-seq) identifies two active Oryco LTR retrotransposons in the rice cultivar Dong**
Long terminal repeat retrotransposons (LTR-RTs) make up a considerable portion of plant genomes. New insertions of these active LTR-RTs modify gene structures and functions and play an important role in genome...
-
Article
Open AccessIncongruence between dominant commensal donor microbes in recipient feces post fecal transplant and response to anti-PD-1 immunotherapy
To understand inter-individual variability of fecal microbe transplantation (FMT) to enhance anti-PD-1 immunotherapy (IT) for melanoma, we analyzed the data sets from two recent publications with a microbial s...
-
Article
Open AccessImpact of the repurposed drug thonzonium bromide on host oral-gut microbiomes
Drug repurposing is a feasible strategy for the development of novel therapeutic applications. However, its potential use for oral treatments and impact on host microbiota remain underexplored. Here, we assess...
-
Article
Open AccessIndividualized recovery of gut microbial strains post antibiotics
To further understand the impact of antibiotics on the gastrointestinal tract microbial community, the intra-individual recovery pattern of specific microbial strains was determined using metagenomic sequencin...
-
Chapter and Conference Paper
Candida–Bacterial Biofilms and Host–Microbe Interactions in Oral Diseases
Oral cavity harbors a complex and highly diverse microbial community. Cross-kingdom interactions between Candida and oral bacteria are critical for their co-existence, which may also affect the course and the sev...
-
Article
The oral microbiota: dynamic communities and host interactions
The dynamic and polymicrobial oral microbiome is a direct precursor of diseases such as dental caries and periodontitis, two of the most prevalent microbially induced disorders worldwide. Distinct microenviron...
-
Article
Targeting microbial biofilms: current and prospective therapeutic strategies
Biofilms harbour complex structural and biological attributes, such as the presence of an extracellular polymeric matrix, physical and chemical heterogeneity a...
-
Article
Comparative analysis of bacterial community-metagenomics in coastal Gulf of Mexico sediment microcosms following exposure to Macondo oil (MC252)
The indigenous bacterial communities in sediment microcosms from Dauphin Island (DI), Petit Bois Island (PB) and Perdido Pass (PP) of the coastal Gulf of Mexico were compared following treatment with Macondo o...
-
Article
Increase in the production of β-carotene in recombinant Escherichia coli cultured in a chemically defined medium supplemented with amino acids
Escherichia coli DH5α strain was selected as the recombinant host, and a chemically defined medium supplemented with amino acids was used instead of a complex medium for the efficient production ...
-
Article
Quercetin production from rutin by a thermostable β-rutinosidase from Pyrococcus furiosus
Pyrococcus furiosus β-glucosidase converted rutin to quercetin and rutinose disaccharide with a ratio of 1:1, with no glucose, l-rhamnose, and isoquercitrin, indicating that the enzyme is a β-rut...
-
Protocol
Protocols to Study the Physiology of Oral Biofilms
The oral cavity harbors several hundred different bacterial species that colonize both hard (teeth) and soft tissues, forming complex populations known as microbial biofilms. It is widely accepted that the phe...
-
Article
Open AccessInfluences of naturally occurring agents in combination with fluoride on gene expression and structural organization of Streptococcus mutans in biofilms
The association of specific bioactive flavonoids and terpenoids with fluoride can modulate the development of cariogenic biofilms by simultaneously affecting the synthesis of exopolysaccharides (EPS) and acid ...
-
Article
Effect of a New Variety of Apis mellifera Propolis onMutans Streptococci
