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  1. Article

    Open Access

    Addition of cariogenic pathogens to complex oral microflora drives significant changes in biofilm compositions and functionalities

    Dental caries is a microbe and sugar-mediated biofilm-dependent oral disease. Of particular significance, a virulent type of dental caries, known as severe early childhood caries (S-ECC), is characterized by t...

    Yuan Liu, Scott G. Daniel, Hye-Eun Kim, Hyun Koo, Jonathan Korostoff in Microbiome (2023)

  2. Article

    Open Access

    A nationwide survey on the implementation of infection prevention and control components in 1442 hospitals in the Republic of Korea: comparison to the WHO Infection Prevention and Control Assessment Framework (IPCAF)

    The current SARS-CoV-2 pandemic continues to underscore the inadequacy of infection prevention and control (IPC) and the importance of its sound establishment in healthcare facilities. The Infection Prevention...

    Yoolwon Jeong, Hyeyoung Joo, Hyunjung Bahk in Antimicrobial Resistance & Infection Contr… (2022)

  3. Article

    Open Access

    Impact of the repurposed drug thonzonium bromide on host oral-gut microbiomes

    Drug repurposing is a feasible strategy for the development of novel therapeutic applications. However, its potential use for oral treatments and impact on host microbiota remain underexplored. Here, we assess...

    Aurea Simon-Soro, Dongyeop Kim, Yong Li, Yuan Liu in npj Biofilms and Microbiomes (2021)

  4. Article

    Open Access

    Impact of national policy on hand hygiene promotion activities in hospitals in Korea

    After the Middle East respiratory syndrome coronavirus outbreak in Korea in 2015, the Government established a strategy for infection prevention to encourage infection control activities in hospitals. The new ...

    Pyoeng Gyun Choe, Jihee Lim, Eun ** Kim in Antimicrobial Resistance & Infection Contr… (2020)

  5. Article

    Open Access

    Individualized recovery of gut microbial strains post antibiotics

    To further understand the impact of antibiotics on the gastrointestinal tract microbial community, the intra-individual recovery pattern of specific microbial strains was determined using metagenomic sequencin...

    Hyunmin Koo, Joseph A. Hakim, David K. Crossman in npj Biofilms and Microbiomes (2019)

  6. No Access

    Article

    The oral microbiota: dynamic communities and host interactions

    The dynamic and polymicrobial oral microbiome is a direct precursor of diseases such as dental caries and periodontitis, two of the most prevalent microbially induced disorders worldwide. Distinct microenviron...

    Richard J. Lamont, Hyun Koo, George Hajishengallis in Nature Reviews Microbiology (2018)

  7. No Access

    Article

    Targeting microbial biofilms: current and prospective therapeutic strategies

  8. Biofilms harbour complex structural and biological attributes, such as the presence of an extracellular polymeric matrix, physical and chemical heterogeneity a...

  9. Hyun Koo, Raymond N. Allan, Robert P. Howlin, Paul Stoodley in Nature Reviews Microbiology (2017)

  10. Article

    Open Access

    Proposed risk factors for infection with multidrug-resistant pathogens in hemodialysis patients hospitalized with pneumonia

    In patients with hemodialysis-associated pneumonia (HDAP), information on both microbiologic features and antimicrobial strategies is limited. The aim of this study is to investigate predictive factors of infe...

    Jae-Uk Song, Hye Kyeong Park, Hyung Koo Kang, Jonghoo Lee in BMC Infectious Diseases (2017)

  11. Article

    Open Access

    Treatment outcomes of adjuvant resectional surgery for nontuberculous mycobacterial lung disease

    Outcomes of antibiotic treatment for lung disease caused by nontuberculous mycobacteria (NTM) are unsatisfactory. The role of adjunctive surgery in the treatment of NTM lung disease is still unclear.

    Hyung Koo Kang, Hye Yun Park, Dohun Kim, Byeong-Ho Jeong in BMC Infectious Diseases (2015)

  12. No Access

    Article

    Comparative analysis of bacterial community-metagenomics in coastal Gulf of Mexico sediment microcosms following exposure to Macondo oil (MC252)

    The indigenous bacterial communities in sediment microcosms from Dauphin Island (DI), Petit Bois Island (PB) and Perdido Pass (PP) of the coastal Gulf of Mexico were compared following treatment with Macondo o...

    Hyunmin Koo, Nazia Mojib, Robert W. Thacker, Asim K. Bej in Antonie van Leeuwenhoek (2014)