7 Result(s)
within
Hyun** Koo
Life Sciences, general
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Article
Open AccessMitochondrial stress activates YAP/TAZ through RhoA oxidation to promote liver injury
Yes-associated protein (YAP) and WW domain-containing transcription regulator protein 1 (WWTR1; also known as TAZ) are the main effectors of the Hippo pathway and their dysregulation contributes to diseases in...
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Article
Open AccessIncongruence between dominant commensal donor microbes in recipient feces post fecal transplant and response to anti-PD-1 immunotherapy
To understand inter-individual variability of fecal microbe transplantation (FMT) to enhance anti-PD-1 immunotherapy (IT) for melanoma, we analyzed the data sets from two recent publications with a microbial s...
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Article
Open AccessImpact of the repurposed drug thonzonium bromide on host oral-gut microbiomes
Drug repurposing is a feasible strategy for the development of novel therapeutic applications. However, its potential use for oral treatments and impact on host microbiota remain underexplored. Here, we assess...
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Article
Open AccessIndividualized recovery of gut microbial strains post antibiotics
To further understand the impact of antibiotics on the gastrointestinal tract microbial community, the intra-individual recovery pattern of specific microbial strains was determined using metagenomic sequencin...
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Article
The oral microbiota: dynamic communities and host interactions
The dynamic and polymicrobial oral microbiome is a direct precursor of diseases such as dental caries and periodontitis, two of the most prevalent microbially induced disorders worldwide. Distinct microenviron...
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Article
Targeting microbial biofilms: current and prospective therapeutic strategies
Biofilms harbour complex structural and biological attributes, such as the presence of an extracellular polymeric matrix, physical and chemical heterogeneity a...
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Article
Open AccessInfluences of naturally occurring agents in combination with fluoride on gene expression and structural organization of Streptococcus mutans in biofilms
The association of specific bioactive flavonoids and terpenoids with fluoride can modulate the development of cariogenic biofilms by simultaneously affecting the synthesis of exopolysaccharides (EPS) and acid ...
