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  1. Article

    Open Access

    Impact of the repurposed drug thonzonium bromide on host oral-gut microbiomes

    Drug repurposing is a feasible strategy for the development of novel therapeutic applications. However, its potential use for oral treatments and impact on host microbiota remain underexplored. Here, we assess...

    Aurea Simon-Soro, Dongyeop Kim, Yong Li, Yuan Liu in npj Biofilms and Microbiomes (2021)

  2. Article

    Open Access

    Individualized recovery of gut microbial strains post antibiotics

    To further understand the impact of antibiotics on the gastrointestinal tract microbial community, the intra-individual recovery pattern of specific microbial strains was determined using metagenomic sequencin...

    Hyunmin Koo, Joseph A. Hakim, David K. Crossman in npj Biofilms and Microbiomes (2019)

  3. No Access

    Article

    The oral microbiota: dynamic communities and host interactions

    The dynamic and polymicrobial oral microbiome is a direct precursor of diseases such as dental caries and periodontitis, two of the most prevalent microbially induced disorders worldwide. Distinct microenviron...

    Richard J. Lamont, Hyun Koo, George Hajishengallis in Nature Reviews Microbiology (2018)

  4. No Access

    Article

    Targeting microbial biofilms: current and prospective therapeutic strategies

  5. Biofilms harbour complex structural and biological attributes, such as the presence of an extracellular polymeric matrix, physical and chemical heterogeneity a...

  6. Hyun Koo, Raymond N. Allan, Robert P. Howlin, Paul Stoodley in Nature Reviews Microbiology (2017)