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Open AccessTREM2 promotes Aβ phagocytosis by upregulating C/EBPα-dependent CD36 expression in microglia
TREM2 plays a critical role in the alleviation of Alzheimer’s disease by promoting Aβ phagocytosis by microglia, but the detailed molecular mechanism underlying TREM2-induced direct phagocytic activity of Aβ r...
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Article
Open AccessBlockade of Axl signaling ameliorates HPV16E6-mediated tumorigenecity of cervical cancer
Axl receptor tyrosine kinase is involved in the tumorigenesis and metastasis of many cancers. Axl expression was markedly higher in human papilloma virus type 16E6 (HPV16E6)-overexpressing HeLa (HE6F) cells an...