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Article
Open AccessDe novo transcriptomic profiling of the clonal Leymus chinensis response to long-term overgrazing-induced memory
Sheepgrass (Leymus chinensis) is one of the dominant grass species present on typical steppes of the Inner Mongolia Plateau. However, L. chinensis has developed a dwarfing phenotype in response to the stressful h...
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Article
Open AccessA novel stearic acid-modified hirudin peptidomimetic with improved pharmacokinetic properties and anticoagulant activity
A novel hirudin isoform 3 mimetic peptide, named peptide S2, has been prepared by introduction of a stearic acid modification. Peptide S2 exhibited superior inhibitory activity to hirulog-1 (Bivariludin) and s...
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Article
Open AccessNext-generation sequencing for molecular diagnosis of lung adenocarcinoma specimens obtained by fine needle aspiration cytology
Identification of multi-gene variations has led to the development of new targeted therapies in lung adenocarcinoma patients and identification of an appropriate patient population with a reliable screening me...