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Article
Activation of MAL2 by RAD21 inhibits the expression of MHC-I in immune evasion of endometrial cancer
CD8+ T cells are the primary mediators of anticancer immunity, and modulation of the CD8+ T cell response has been a central focus of immunotherapy to treat cancer. When CD8+ T cells specifically recognize antige...
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Article
Open AccessThe perceived impact of PISA on student learning in schools in a local Chinese context
The increasing concerns of the impact of the Programmes for International Student Assessment (PISA) on education policymaking along with its global reach call for the need of evaluating PISA’s impact on studen...
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Article
Open AccessA three-dimensional quantitative assessment on bony growth and symmetrical recovery of mandible after decompression for unicystic ameloblastoma
Unicystic ameloblastoma (UAM) of the jaw can be effectively reduced in volume through decompression, which promotes bone regeneration and restores jaw symmetry. This study quantitatively evaluated changes in m...
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Article
Open AccessUltrasound quantification of pleural effusion volume in supine position: comparison of three model formulae
To investigate the accuracy of three model formulae for ultrasound quantification of pleural effusion (PE) volume in patients in supine position.
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Article
TYMS Knockdown Suppresses Cells Proliferation, Promotes Ferroptosis via Inhibits PI3K/Akt/mTOR Signaling Pathway Activation in Triple Negative Breast Cancer
Triple-negative breast cancer (TNBC) is characterized by a grim prognosis and numerous challenges. The objective of our study was to examine the role of thymidylate synthase (TYMS) in TNBC and its impact on fe...
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Article
Open AccessNon-homologous end joining shapes the genomic rearrangement landscape of chromothripsis from mitotic errors
Mitotic errors generate micronuclei entrap** mis-segregated chromosomes, which are susceptible to catastrophic fragmentation through chromothripsis. The reassembly of fragmented chromosomes by error-prone DN...
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Article
KNN-GCN: A Deep Learning Approach for Slope-Unit-Based Landslide Susceptibility Map** Incorporating Spatial Correlations
Landslides pose a significant risk to human life and property, making landslide susceptibility map** (LSM) a crucial component of landslide risk assessment. However, spatial correlations among map** units ...
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Article
A New Approach to the Calculation of Bond Work Index with Mixed Grinding Media
Grinding media influence the energy consumption and efficiency of the grinding process during the calculation of the Bond Work index (BWi), a well-known method for selecting comminution equipment, evaluating m...
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Article
Open AccessBoswellia carterii n-hexane extract suppresses breast cancer growth via induction of ferroptosis by downregulated GPX4 and upregulated transferrin
Breast cancer (BC) remains a significant health concern for women globally, prompting the relentless pursuit of novel therapeutic modalities. As a traditional Chinese medicine, Boswellia carterii has been extensi...
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Article
Optimization and evaluation of facial recognition models for Williams-Beuren syndrome
Williams-Beuren syndrome (WBS) is a rare genetic disorder characterized by special facial gestalt, delayed development, and supravalvular aortic stenosis or/and stenosis of the branches of the pulmonary artery...
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Article
The aging and color development of writing in paper archives
The most important value of archives lies in the handwritten information they record. However, during the storage process, handwriting may change color or fade due to the influence of the storage environment, ...
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Article
Open AccessMetagenomic next-generation sequencing reveals co-infection with Legionella pneumophila and Fusobacterium necrophorum in a patient with severe pneumonia: a case report
Legionella pneumonia is one of the most severe types of atypical pneumonia, impairing multiple organ systems, posing a threat to life. Diagnosing Legionella pneumonia is challenging due to difficulties in cult...
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Article
Open AccessAutomated, IMU-based spine angle estimation and IMU location identification for telerehabilitation
Telerehabilitation is a promising avenue for improving patient outcomes and expanding accessibility. However, there is currently no spine-related assessment for telerehabilitation that covers multiple exercises.
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Article
Grey prediction model based on Euler equations and its application in highway short-term traffic flow
As the urbanization rate in China has continued to increase, the highway congestion problem has become more severe, significantly reducing the efficiency of traffic operations. To accurately predict highway sh...
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Article
An anorthositic meteorite supporting an ancient magma ocean on Vesta
The widespread occurrence of ferroan anorthosites and other magmatic rock types in Apollo lunar samples directly contributed to the construction and development of modern planetary formation models. If the Ves...
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Article
Insight into the Permeability and Microstructure Evolution Mechanism of the Sliding Zone Soil: A Case Study from the Huangtupo Landslide, Three Gorges Reservoir, China
A large number of laboratory investigations related to the permeability have been conducted on the sliding zones. Yet little attention has been paid to the particular sliding zones of the slide-prone Badong Fo...
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Article
Open AccessPD-1/PD-L1 inhibitors for early and middle stage microsatellite high-instability and stable colorectal cancer: a review
Programmed cell death receptor 1 (PD-1) and programmed cell death ligand 1 (PD-L1) are important immune checkpoint molecules that contribute to tumor immune evasion. However, the main treatment modalities for ...
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Article
Open AccessTopological alterations in white matter anatomical networks in cervical dystonia
Accumulating neuroimaging evidence indicates that patients with cervical dystonia (CD) have changes in the cortico-subcortical white matter (WM) bundle. However, whether these patients’ WM structural networks ...
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Article
Open AccessRegional structural abnormalities in thalamus in idiopathic cervical dystonia
The thalamus has a central role in the pathophysiology of idiopathic cervical dystonia (iCD); however, the nature of alterations occurring within this structure remain largely elusive. Using a structural magne...
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Article
Open AccessEffect of baicalin on eradicating biofilms of bovine milk derived Acinetobacter lwoffii
Acinetobacter lwoffii (A.lwoffii) is a serious zoonotic pathogen that has been identified as a cause of infections such as meningitis, bacteremia and pneumonia. In recent years, the infection rate and detection r...
