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  1. No Access

    Article

    Utilizing the Neural Renderer for Accurate 3D Face Reconstruction from a Single Image

    Recently, deep learning-based methods have shown significant results in 3D face reconstruction. By harnessing the power of convolutional neural networks, significant progress has been made in recovering 3D fac...

    Wei Wei, Danni Zhang, Huichen Wang, **aodong Duan, Chen Guo in Neural Processing Letters (2023)

  2. No Access

    Chapter and Conference Paper

    Efficient Numerical Methodology for the Determination of Thermal Conductivity of Asphalt Mixtures

    Despite the importance of the thermal conductivity (k) to the study of pavement thermal behaviors, it is still a challenging task for engineers to come up with an efficient method for its determination without...

    Huichen Wang, L. Chu, Lei He, T. F. Fwa in Road and Airfield Pavement Technology (2022)

  3. No Access

    Protocol

    Plasmid-Based Assays for DNA End-Joining In Vitro

    Double-strand breaks (DSBs) disrupt DNA integrity and cause genomic instability and cancer, mutations, or cell death. Among the pathways utilized by cells of higher eukaryotes to repair this lesion, nonhomolog...

    George Iliakis, Bustanur Rosidi, Minli Wang, Huichen Wang in DNA Repair Protocols (2006)

  4. No Access

    Article

    Caffeine inhibits homology-directed repair of I-SceI-induced DNA double-strand breaks

    We recently reported that two Chinese hamster mutants deficient in the RAD51 paralogs XRCC2 and XRCC3 show reduced radiosensitization after treatment with caffeine, thus implicating homology-directed repair (HDR)...

    Huichen Wang, Wilfried Boecker, Hongyan Wang, **ang Wang, Jun Guan… in Oncogene (2004)

  5. No Access

    Article

    DNA damage checkpoint control in cells exposed to ionizing radiation

    Damage induced in the DNA after exposure of cells to ionizing radiation activates checkpoint pathways that inhibit progression of cells through the G1 and G2 phases and induce a transient delay in the progress...

    George Iliakis, Ya Wang, Jun Guan, Huichen Wang in Oncogene (2003)

  6. No Access

    Article

    hTERT associates with human telomeres and enhances genomic stability and DNA repair

    Ectopic expression of telomerase in telomerase-silent cells is sufficient to overcome senescence and to extend cellular lifespan. We show here that the catalytic subunit of human telomerase (hTERT) crosslinks ...

    Girdhar G Sharma, Arun Gupta, Huichen Wang, Harry Scherthan, Sonu Dhar… in Oncogene (2003)

  7. No Access

    Article

    Efficient rejoining of radiation-induced DNA double-strand breaks in vertebrate cells deficient in genes of the RAD52 epistasis group

    Rejoining of ionizing radiation (IR) induced DNA DSBs usually follows biphasic kinetics with a fast (t50: 5–30 min) component attributed to DNA-PK-dependent non-homologous endjoining (NHEJ) and a slow (t50: 1–20 ...

    Huichen Wang, Zhao-Chong Zeng, Tu-Anh Bui, Eiichiro Sonoda, Minoru Takata… in Oncogene (2001)

  8. No Access

    Article

    BRCA1 proteins are transported to the nucleus in the absence of serum and splice variants BRCA1a, BRCA1b are tyrosine phosphoproteins that associate with E2F, cyclins and cyclin dependent kinases

    BRCA1, a familial breast and ovarian cancer susceptibility gene encodes nuclear phosphoproteins that function as tumor suppressors in human breast cancer cells. Previously, we have shown that overexpression of...

    Huichen Wang, Ningsheng Shao, Qing Ming Ding, Jian-qi Cui, E Shyam P Reddy… in Oncogene (1997)