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Article
Interleukin-6 Inhibits Expression of miR-204-5p, a Regulator of Oligodendrocyte Differentiation: Involvement of miR-204-5p in the Prevention of Chemical-Induced Oligodendrocyte Impairment
Oligodendrocytes (OLs) form myelin sheaths around axons in the central nervous system (CNS) facilitate the propagation of action potentials. The studies have shown that the differentiation and maturation of OL...
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Article
Potential of semen coicis in enhancing the anti-tumor effects of PD-1 inhibitor on A549 cell lines by blocking the PI3K-AKT-mTOR pathway
The objective of this research was to investigate how the combination of semen coicis extract and PD-1 inhibitors can potentially work together to enhance the anti-tumor effects, with a focus on understanding ...
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Article
Open AccessBronchial epithelial transcriptomics and experimental validation reveal asthma severity-related neutrophilc signatures and potential treatments
Airway epithelial transcriptome analysis of asthma patients with different severity was used to disentangle the immune infiltration mechanisms affecting asthma exacerbation, which may be advantageous to asthma...
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Article
Open AccessAuthor Correction: Hericium erinaceus mycelium and its small bioactive compounds promote oligodendrocyte maturation with an increase in myelin basic protein
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Article
Open AccessHericium erinaceus mycelium and its small bioactive compounds promote oligodendrocyte maturation with an increase in myelin basic protein
Oligodendrocytes (OLs), myelin-producing glia in the central nervous system (CNS), produce a myelin extension that enwraps axons to facilitate action potential propagation. An effective approach to induce olig...
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Article
Open AccessIntermittent peripheral exposure to lipopolysaccharide induces exploratory behavior in mice and regulates brain glial activity in obese mice
Consecutive peripheral immune challenges can modulate the responses of brain resident microglia to stimuli. High-fat diet (HFD) intake has been reported to stimulate the activation of astrocytes and microglia ...
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Article
Open AccessChronic exposure to high fat diet triggers myelin disruption and interleukin-33 upregulation in hypothalamus
Hypothalamic inflammation including astrogliosis and microglia activation occurs after intake of high fat diet (HFD) in rodent models or in obese individuals. However, the effect of chronic HFD feeding on olig...
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Chapter and Conference Paper
Pushing Decision Points Backward to the Latest Possible Positions with a Workflow Log
Currently, enterprises face more competitive and complex environments than ever before. Companies would suffer devastating setbacks if business changes were ignored. Enterprises could leverage competitive adva...
