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    Article

    Influence of Incomplete Soil Plugs on Bearing Capacities of Bucket Foundations in Clay

    Due to the uneven seabed and heaving of soil during pum**, incomplete soil plugs may occur during the installation of bucket foundations, and the impacts on the bearing capacities of bucket foundations need ...

    Hui-shan Li, Run Liu, Xu Yang, Ji-jian Lian in China Ocean Engineering (2024)

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    Article

    Enhanced Efficacy of Immunization with a Foot-and-Mouth Disease Multi-Epitope Subunit Vaccine Using Mannan-Decorated Inulin Microparticles

    Despite the many advantages of recombinant subunit vaccines, they have critical weaknesses that include a low efficacy for promoting cellular and humoral immune responses against antigens because of their poor...

    So-Yeon Yoon, Sang-Kee Kang, Ho-Bin Lee in Tissue Engineering and Regenerative Medici… (2020)

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    Chapter

    Degradable Polyethylenimine-Based Gene Carriers for Cancer Therapy

    Gene therapy using recombinant DNA or gene silencing using siRNA have become a prominent area of research in cancer therapy. However, their use in clinical applications is limited due to overall safety concern...

    Hu-Lin Jiang, Mohammad Ariful Islam, Lei **ng in Polymeric Gene Delivery Systems (2018)

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    Article

    Degradable Polyethylenimine-Based Gene Carriers for Cancer Therapy

    Gene therapy using recombinant DNA or gene silencing using siRNA have become a prominent area of research in cancer therapy. However, their use in clinical applications is limited due to overall safety concern...

    Hu-Lin Jiang, Mohammad Ariful Islam, Lei **ng in Topics in Current Chemistry (2017)

  5. Article

    Open Access

    Trigger factor assisted soluble expression of recombinant spike protein of porcine epidemic diarrhea virus in Escherichia coli

    Porcine epidemic diarrhea virus (PEDV) is a highly contagious enteric pathogen of swine. The spike glycoprotein (S) of PEDV is the major immunogenic determinant that plays a pivotal role in the induction of ne...

    Da-Chuan Piao, Do-Woon Shin, In-Seon Kim, Hui-Shan Li, Seo-Ho Oh in BMC Biotechnology (2016)

  6. Article

    Open Access

    Soluble RANKL expression in Lactococcus lactis and investigation of its potential as an oral vaccine adjuvant

    To initiate mucosal immune responses, antigens in the intestinal lumen must be transported into gut-associated lymphoid tissue through M cells. Recently, it has been increasingly recognized that receptor activ...

    Jeong-In Kim, Tae-Eun Park, Sushila Maharjan, Hui-Shan Li, Ho-Bin Lee in BMC Immunology (2015)

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    Article

    Production of Recombinant Human Growth Hormone Conjugated with a Transcytotic Peptide in Pichia pastoris for Effective Oral Protein Delivery

    Among the possible delivery routes, the oral administration of a protein is simple and achieves high patient compliance without pain. However, the low bioavailability of a protein drug in the intestine due to ...

    Jun-Yeong Lee, Sang-Kee Kang, Hui-Shan Li, Chang-Yun Choi in Molecular Biotechnology (2015)

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    Chapter and Conference Paper

    Construction of the Supplier Evaluation Index System Based on Supply Chain

    In order to make the supply chain select the best suppliers, the supplier system is defined and analyzed, finding out the main influencing factors. An index of estimation system is established, and synthesis e...

    Hui-shan Li, Chun-xian Wang, Chun-he Zhang in International Asia Conference on Industria… (2013)