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Article
Open AccessThe clinical effectiveness of sivelestat in treating sepsis patients with both acute respiratory distress syndrome and septic cardiomyopathy
We aimed to assess the efficacy of the neutrophil elastase inhibitor, sivelestat, in the treatment of sepsis-induced acute respiratory distress syndrome (ARDS) and septic cardiomyopathy (SCM).
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Article
Open AccessCircular RNA MKLN1 promotes epithelial-mesenchymal transition in pulmonary fibrosis by regulating the miR-26a/b-5p/CDK8 axis in human alveolar epithelial cells and mice models
Pulmonary fibrosis involves destruction of the lung parenchyma and extracellular matrix deposition. Effective treatments for pulmonary fibrosis are lacking and its pathogenesis is still unclear. Studies have f...
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Article
Open AccessFactors affecting medical students’ intention to use Rain Classroom: a cross-sectional survey
Rain Classroom was one of the most popular online learning platforms in Chinese higher education during the pandemic. However, there is little research on user intention under the guidance of technology accept...
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Article
Open AccessPreparation and adsorption properties of magnetic chitosan/sludge biochar composites for removal of Cu2+ ions
The magnetic chitosan/sludge biochar composite adsorbent was prepared using chitosan, Fe3O4, and sludge biochar as raw materials. The composite adsorbent was able to achieve rapid solid–liquid separation under an...
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Article
Single-cell RNA sequencing combined with single-cell proteomics identifies the metabolic adaptation of islet cell subpopulations to high-fat diet in mice
Islets have complex heterogeneity and subpopulations. Cell surface markers representing alpha, beta and delta cell subpopulations are urgently needed for investigations to explore the compositional changes of ...
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Article
Open AccessEfficacy of erector spinae plane block for postoperative analgesia lumbar surgery: a systematic review and meta-analysis
The erector spinae plane (ESP) block is a newly defined regional anesthesia technique first described in 2016. The aim of this meta-analysis is to assess the efficacy of ESP block in improving analgesia follow...
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Article
Open AccessOptical sensor using space-domain active fiber cavity ringdown technique
A novel active fiber cavity ringdown (FCRD) technique using frequency-shifted interferometry (FSI) is proposed for the first time. Using this scheme, external parameters can be monitored in the space domain by...
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Article
Open AccessAdipose-derived mesenchymal stem cells with hypoxic preconditioning improve tenogenic differentiation
Adipose-derived mesenchymal stem cells (ADSCs), as seed cells for tendon tissue engineering, are promising for tendon repair and regeneration. But for ADSCs, diverse oxygen tensions have different stimulatory ...
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Article
Open AccessUsing entropy-driven amplifier circuit response to build nonlinear model under the influence of Lévy jump
Bioinformatics is a subject produced by the combination of life science and computer science. It mainly uses computer technology to study the laws of biological systems. The design and realization of DNA circu...
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Article
Open AccessOpen reduction and locked compression plate fixation, with or without allograft strut, for periprosthetic fractures in patients who had a well-fixed femoral stem: a retrospective study with an average 2-year follow-up
The use of cortical strut allograft has not been determined for Vancouver type B1 or C fracture. This study aimed to evaluate the short-term efficacy of locking compression plating with or without cortical str...
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Article
Open AccessCorrection to: Defect Detection in the Winding Layer of CNG Composite-Wound Cylindersvirtue of minimal mechanism is that it allows
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Article
Open AccessDefect Detection in the Winding Layer of CNG Composite-Wound Cylindersvirtue of minimal mechanism is that it allows
Natural gas vehicles have been widely used around the world as a mode of green transportation. The defect detection method for a vehicle cylinder, which is the energy storage component of a natural gas vehicle...
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Open AccessAuthor Correction: A concise access to bridged [2,2,1] bicyclic lactones with a quaternary stereocenter via stereospecific hydroformylation
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Article
Open AccessEffects of hypoxia on Achilles tendon repair using adipose tissue-derived mesenchymal stem cells seeded small intestinal submucosa
The study was performed to evaluate the feasibility of utilizing small intestinal submucosa (SIS) scaffolds seeded with adipose-derived mesenchymal stem cells (ADMSCs) for engineered tendon repairing rat Achil...
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Article
Open AccessClinical characteristics and outcomes of critically ill patients with acute COVID-19 with Epstein-Barr virus reactivation
Our goal is to further elucidate the clinical condition and prognosis of patients with severe acute COVID-19 with EBV reactivation.
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Article
Open AccessA concise access to bridged [2,2,1] bicyclic lactones with a quaternary stereocenter via stereospecific hydroformylation
Chiral bridged [2,2,1] bicyclic lactones are privileged structural units in pharmaceutics and bioactive nature products. However, the synthetic methods for these compounds are rare. Here we report an efficient...
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Article
Open AccessSpecies and genetic variability of sweet potato viruses in China
China is the world’s largest producer of sweet potato (Ipomoea batatas (L.) Lam.). Considering that there are numerous sweet potato-producing regions in China and sweet potato is a vegetatively propagated crop, t...
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Article
Open AccessEnhancing stability by trap** palladium inside N-heterocyclic carbene-functionalized hypercrosslinked polymers for heterogeneous C-C bond formations
Catalyst deactivation caused by the aggregation of active metal species in the reaction process poses great challenges for practical applications of supported metal catalysts in solid-liquid catalysis. Herein,...
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Article
Open AccessWrist tuberculosis-experience from eighteen cases: a retrospective study
Wrist tuberculosis is a rare disease, which is easy to be misdiagnosed, leading to delayed treatment and poor prognosis. In this study, the clinical manifestations, diagnosis, treatment, and prognosis of 18 ca...
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Article
Open AccessA 29 Mainland Chinese cohort of patients with Phelan–McDermid syndrome: genotype–phenotype correlations and the role of SHANK3 haploinsufficiency in the important phenotypes
Phelan–McDermid syndrome (PMS) or 22q13 deletion syndrome is a rare developmental disorder characterized by hypotonia, developmental delay (DD), intellectual disability (ID), autism spectrum disorder (ASD) and...
