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Article
Open AccessAction mechanism of corticosteroids to aggravate Guillain-Barré syndrome
Corticosteroids have been proved to be ineffective for Guillain-Barré syndrome, but the mechanism remains unknown. In a rabbit model of axonal Guillain-Barré syndrome, treatment with corticosteroids significan...
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Article
Open AccessCrystal Structure of Human SSRP1 Middle Domain Reveals a Role in DNA Binding
SSRP1 is a subunit of the FACT complex, an important histone chaperone required for transcriptional regulation, DNA replication and damage repair. SSRP1 also plays important roles in transcriptional regulation...
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Article
Open AccessSilicon-oriented regio- and enantioselective rhodium-catalyzed hydroformylation
Hydroformylation of 1,2-disubstituted alkenes usually occurs at the α position of the directing heteroatom such as oxygen atom and nitrogen atom. By contrast, to achieve hydroformylation on the β position of t...
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Article
Open AccessEnantioselective Rhodium-Catalyzed Cycloisomerization of 1,6-Allenynes to access 5/6-Fused Bicycle[4.3.0]nonadienes
Transition-metal-catalyzed cycloisomerization of 1,n-allenynes represents a powerful synthetic tool to rapidly assemble complex polycyclic skeletons from simple linear substrates. Nevertheless, there are no re...
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Article
Open AccessImplementing digital computing with DNA-based switching circuits
DNA strand displacement reactions (SDRs) provide a set of intelligent toolboxes for develo** molecular computation. Whereas SDR-based logic gate circuits have achieved a high level of complexity, the scale-u...
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Article
Open AccessEnhancing stability by trap** palladium inside N-heterocyclic carbene-functionalized hypercrosslinked polymers for heterogeneous C-C bond formations
Catalyst deactivation caused by the aggregation of active metal species in the reaction process poses great challenges for practical applications of supported metal catalysts in solid-liquid catalysis. Herein,...
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Open AccessA concise access to bridged [2,2,1] bicyclic lactones with a quaternary stereocenter via stereospecific hydroformylation
Chiral bridged [2,2,1] bicyclic lactones are privileged structural units in pharmaceutics and bioactive nature products. However, the synthetic methods for these compounds are rare. Here we report an efficient...
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Article
Open AccessAuthor Correction: A concise access to bridged [2,2,1] bicyclic lactones with a quaternary stereocenter via stereospecific hydroformylation
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Article
Open AccessOptical sensor using space-domain active fiber cavity ringdown technique
A novel active fiber cavity ringdown (FCRD) technique using frequency-shifted interferometry (FSI) is proposed for the first time. Using this scheme, external parameters can be monitored in the space domain by...
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Article
Open AccessPreparation and adsorption properties of magnetic chitosan/sludge biochar composites for removal of Cu2+ ions
The magnetic chitosan/sludge biochar composite adsorbent was prepared using chitosan, Fe3O4, and sludge biochar as raw materials. The composite adsorbent was able to achieve rapid solid–liquid separation under an...