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  1. No Access

    Article

    Effect of Bricks-and-Mortar Architecture on Fracture Behavior of SiCp/Al Composite: A Finite Element Analysis

    The metal-matrix composites (MMCs) with biomimetic bricks-and-mortar architectures have been experimentally demonstrated to exhibit excellent strength-ductility match. Here, biomimetic bricks-and-mortar archit...

    **ang Gao, **aonan Lu, Xuexi Zhang, Mingfang Qian, Aibin Li in Applied Composite Materials (2024)

  2. No Access

    Article

    Novel PATL2 variants cause female infertility with oocyte maturation defect

    Oocyte maturation defect (OOMD) is a rare cause of in vitro fertilization failure characterized by the production of immature oocytes. Compound heterozygous or homozygous PATL2 mutations have been associated with...

    Hua-ying Hu, Ge-han Zhang, Wei-fen Deng in Journal of Assisted Reproduction and Genet… (2024)

  3. Article

    Open Access

    CRISPR screens reveal convergent targeting strategies against evolutionarily distinct chemoresistance in cancer

    Resistance to chemotherapy has been a major hurdle that limits therapeutic benefits for many types of cancer. Here we systematically identify genetic drivers underlying chemoresistance by performing 30 genome-...

    Chunge Zhong, Wen-Jie Jiang, Yingjia Yao, Zexu Li, You Li in Nature Communications (2024)

  4. No Access

    Article

    Effectiveness of Lianhua Qingwen Granule and **gyin Gubiao Prescription in Omicron BA.2 Infection and Hospitalization: A Real-World Study of 56,244 Cases in Shanghai, China

    To examine the effectiveness of Chinese medicine (CM) Lianhua Qingwen Granule (LHQW) and **gyin Gubiao Prescription (JYGB) in asymptomatic or mild patients with Omicron infection in the shelter hospital.

    Yu-jie Zhang, Guo-jian Liu, Han Zhang, Chen Liu in Chinese Journal of Integrative Medicine (2024)

  5. Article

    Open Access

    Kinetic nitrogen isotope effects of 18 amino acids degradation during burning processes

    Understanding the nitrogen isotopic variations of individual amino acids (AAs) is essential for utilizing the nitrogen isotope values of individual amino acids (δ15N-AA) as source indicators to identify proteinac...

    Ren-Guo Zhu, Hua-Yun **ao, Meiju Yin, Hao **ao, Zhongkui Zhou in Scientific Reports (2024)

  6. No Access

    Article

    Genomic structures of insulin-like growth factor from golden pompano (Trachinotus ovatus) and their expression responses to the feed types

    Golden pompano is an important aquaculture product in the coastal regions of southern China, which is highly dependent on insulin-like growth factor (IGF) for various biological processes. The cDNAs of ToIGF1, To...

    Bo Liu, Yin-Yin Liang, Hua-Yang Guo, Bao-Suo Liu in Fish Physiology and Biochemistry (2024)

  7. Article

    Open Access

    Correlation between hemoglobin and the risk of common malignant tumors: a 1999–2020 retrospective analysis and causal association analysis

    The role of hemoglobin (HGB) in common malignant tumors remains unclear.

    Guo-Sheng Li, Tao Huang, **g-**ao Li, Jun Liu, **ang Gao, Nuo Yang in BMC Cancer (2024)

  8. No Access

    Article

    Structural basis of tolvaptan binding to the vasopressin V2 receptor

    The vasopressin V2 receptor (V2R) is a validated therapeutic target for autosomal dominant polycystic kidney disease (ADPKD), with tolvaptan being the first FDA-approved antagonist. Herein, we used Gaussian accel...

    Hong-li Liu, Hai-yang Zhong, Yi-xiao Zhang, Hua-rui Xue in Acta Pharmacologica Sinica (2024)

  9. Article

    Open Access

    Radiomic analysis based on magnetic resonance imaging for the prediction of VEGF expression in hepatocellular carcinoma patients

    The purpose of this study was to investigate the ability of radiomic characteristics of magnetic resonance images to predict vascular endothelial growth factor (VEGF) expression in hepatocellular carcinoma (HC...

    Cui Yang, Ze-Ming Zhang, Zhang-** Zhao, Zhi-Qing Wang, **g Zheng in Abdominal Radiology (2024)

  10. No Access

    Article

    A global survey on the use of the international classification of diseases codes for metabolic dysfunction-associated fatty liver disease

    With the implementation of the 11th edition of the International Classification of Diseases (ICD-11) and the publication of the metabolic dysfunction-associated fatty liver disease (MAFLD) nomenclature in 2020...

    Huai Zhang, Giovanni Targher, Christopher D. Byrne in Hepatology International (2024)

  11. Article

    Open Access

    Combined associations of visceral adipose tissue and adherence to a Mediterranean lifestyle with T2D and diabetic microvascular complications among individuals with prediabetes

    It’s unclear if excess visceral adipose tissue (VAT) mass in individuals with prediabetes can be countered by adherence to a Mediterranean lifestyle (MEDLIFE). We aimed to examine VAT mass, MEDLIFE adherence, ...

    Hao-Wen Chen, Kuan Liu, Bi-Fei Cao, Qi Zhong, Rui Zhou in Cardiovascular Diabetology (2024)

  12. Article

    Open Access

    An intelligent threshold selection method to improve orbital angular momentum-encoded quantum key distribution under turbulence

    High-dimensional quantum key distribution (HD-QKD) encoded by orbital angular momentum (OAM) presents significant advantages in terms of information capacity. However, perturbations caused by free-space atmosp...

    Jia-Hao Li, Jie Tang, **ng-Yu Wang, Yang Xue, Hui-Cun Yu in EPJ Quantum Technology (2024)

  13. Article

    Open Access

    Gastroenteropancreatic neuroendocrine neoplasms: current development, challenges, and clinical perspectives

    Neuroendocrine neoplasms (NENs) are highly heterogeneous and potentially malignant tumors arising from secretory cells of the neuroendocrine system. Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) a...

    **an-Bin Zhang, Yi-Bao Fan, Rui **g, Mikiyas Amare Getu in Military Medical Research (2024)

  14. No Access

    Article

    Anti-adipogenesis and anti-obesity potential of alliin mediated by modulating glycolipid metabolism via activating PPARγ signaling

    Garlic exhibits hypolipidemic, hypoglycemic, and cardiovascular benefits. The inconsistent results of garlic preparations on adipogenesis have caused more confusion in the public and academia. The compounds re...

    Ming-Yan Yang, Yu-**g Liu, Mei-Hua Zheng in Naunyn-Schmiedeberg's Archives of Pharmaco… (2024)

  15. No Access

    Article

    Parameter optimization of the observation system for the South Yellow Sea strong shielding layer based on seismic illumination analysis

    The seismic data of the Laoshan Uplift in the South Yellow Sea Basin reveal a low signal-to-noise ratio and low reflection signal energy in the deep Mesozoic–Paleozoic strata. The main reason is that the Mesoz...

    Jia-Jia Yang, Jian-Wen Chen, Fu-Qiang Huang, Zhong-Hui Yan in Applied Geophysics (2024)

  16. No Access

    Article

    Itemized determination of As, Sb, Bi, Se, and Ge in graphite sample by HG-AFS with high-temperature microwave digestion

    In this paper, we optimized a method for fast and accurate determination of five impurity elements (As, Sb, Bi, Se, and Ge) in graphite samples to overcome the shortcomings of existing methods, such as complic...

    Jian-Wei Meng, Li-** Wang, Ai-Qin Liu, Yan-Qiao Hu, Li Wei in Analytical Sciences (2024)

  17. No Access

    Article

    Identification and Validation of SLC9A2 as A Potential Tumor Suppressor in Colorectal Cancer: Integrating Bioinformatics Analysis with Experimental Confirmation

    To uncover the mechanisms underlying the development of colorectal cancer (CRC), we applied bioinformatic analyses to identify key genes and experimentally validated their possible roles in CRC onset and progr...

    Yan-min Liu, Tie-cheng Yang, **ao-chang Fang, Li-jie Yang in Current Medical Science (2024)

  18. No Access

    Article

    Amorphous NiMo3S13/nickel foam integrated anode for lithium-ion batteries

    Although crystalline anode materials with long-range ordered lattice structure are in favor of facilitating the electron transfer, their structures are easily disrupted during long-term cycling due to the cont...

    Ming-**n Shi, Min Wu, Shan-Shan **ao, Shan-** Liu, Rui-Qi Yao, Ying-Qi Li in Tungsten (2024)

  19. No Access

    Article

    A PRISMA meta-analysis for diagnostic value of microRNA-21 in head and neck squamous cell carcinoma along with bioinformatics research

    The use of miR-21 expression remains vague in diagnosis of head and neck squamous cell carcinoma (HNSCC). This study aimed to systematically evaluate the diagnostic potential of the miR-21 expression in patien...

    Chen-xi Li, Ying Su, Zheng-ye Wang, Hui Liu in Oral and Maxillofacial Surgery (2024)

  20. Article

    Open Access

    Association of sudden sensorineural hearing loss with meteorological factors: a time series study in Hefei, China, and a literature review

    Air pollution can cause disease and has become a major global environmental problem. It is currently believed that air pollution may be related to the progression of SSNHL. As a rapidly develo** city in rece...

    **ao-Bo Li, Yan-Xun Han, Zi-Yue Fu in Environmental Science and Pollution Resear… (2024)

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