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  1. Article

    Open Access

    Vitamin D receptor gene polymorphism predicts left ventricular hypertrophy in maintenance hemodialysis

    To verify that the single nucleotide polymorphisms (SNP) of vitamin D receptor (VDR) may lead to genetic susceptibility to left ventricular hypertrophy (LVH), the present study was designed to study four SNPs ...

    Bingman Liu, Qingqing Yang, Liangyu Zhao, Hua Shui, **aoyun Si in BMC Nephrology (2022)

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  2. Article

    Open Access

    MiR-615 Agomir Encapsulated in Pluronic F-127 Alleviates Neuron Damage and Facilitates Function Recovery After Brachial Plexus Avulsion

    Brachial plexus avulsion (BPA) is a devastating traumatic peripheral nerve injury complicated with paralysis of the upper extremity. We previously reported that leucine-rich repeat and immunoglobulin-like doma...

    Kangzhen Chen, Lu Ding, Hua Shui, Yinru Liang… in Journal of Molecular Neuroscience (2022)

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  3. Article

    Open Access

    microRNA-29b prevents renal fibrosis by attenuating renal tubular epithelial cell–mesenchymal transition through targeting the PI3K/AKT pathway

    This study aimed to investigate the effects of miR-29b on renal interstitial fibrosis in the obstructed kidney of mouse with unilateral ureteral obstruction (UUO) via inhibiting phosphatidylinositol 3-kinase/p...

    Shuang Hu, Hongtao Hu, Rui Wang, Hong He, Hua Shui in International Urology and Nephrology (2021)

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  4. Article

    Open Access

    Evaluation of serum free fatty acids in chronic renal failure: evidence from a rare case with undetectable serum free fatty acids and population data

    Free fatty acid (FFA) accumulation in proximal tubules plays a fundamental role in the progress of kidney disease. Here, we reported a rare case with undetectable serum FFAs and further evaluated the changes o...

    Zhen-**an Liu, Qian Hong, Ding-Hui Peng, Ying Yang… in Lipids in Health and Disease (2019)

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  5. No Access

    Article

    Calcitriol regulates angiotensin-converting enzyme and angiotensin converting-enzyme 2 in diabetic kidney disease

    To investigate the effects of calcitriol on angiotensin-converting enzyme (ACE) and ACE2 in diabetic nephropathy. Streptozotocin (STZ) induced diabetic rats were treated with calcitriol for 16 weeks. ACE/ACE2 ...

    Mei Lin, ** Gao, Tianya Zhao, Lei He, Mengshi Li, Yaoyao Li… in Molecular Biology Reports (2016)

  6. No Access

    Article

    Fluvastatin inhibits angiotensin II-induced nuclear factor kappa B activation in renal tubular epithelial cells through the p38 MAPK pathway

    3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors has been shown to reduce the progression of renal disease independent of cholesterol-lowering effect, but the mechanism of potential protect...

    ** Gao, **aoyan Wu, Hua Shui, Ruhan Jia in Molecular Biology Reports (2012)

  7. No Access

    Article

    Mycophenolic acid inhibits albumin-induced MCP-1 expression in renal tubular epithelial cells through the p38 MAPK pathway

    Proteinuria is a well-established exacerbating factor in chronic kidney disease. Although the mechanisms of albumin-induced tubulointerstitial damage have been extensively studied, the influence of mycophenoli...

    Hua Shui, ** Gao, **aoyun Si, Guohua Ding in Molecular Biology Reports (2010)