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  1. No Access

    Article

    Multi-task Chinese aspect-based sentiment analysis framework for service improvement: a case study on BNB reviews

    User-generated content has become an essential factor influencing customer choice in the selection of hotel and bed and breakfast (BNB) accommodation. It is important for entrepreneurs to effectively analyze c...

    Li-Chen Cheng, Hsin-Yi Huang, Yu-Wei Huang in Electronic Commerce Research (2024)

  2. Article

    Open Access

    Comparing transfusion reactions between pre-storage and post-storage leukoreduced apheresis platelets: an analysis using propensity score matching

    Transfusion reactions induced by platelet transfusions may be reduced and alleviated by leukocyte reduction of platelets. Although leukoreduction of apheresis platelets can be performed either pre-storage or p...

    Sheng-Hsuan Chien, Hsin-Yi Huang, Ying-Ju Chen, Yu-Chen Tsai in Annals of Hematology (2024)

  3. No Access

    Article

    Low-dose prasugrel versus standard-dose ticagrelor in east Asian patients with acute coronary syndrome

    Low-dose prasugrel demonstrated a similar effectiveness profile to clopidogrel in East Asian ACS patients, but its comparison with another new-generation potent P2Y12 inhibitor, ticagrelor, remains unclear. To co...

    Yee-Jen Wu, Chien-Chih Wu, Hsin-Yi Huang in Journal of Thrombosis and Thrombolysis (2024)

  4. Article

    Open Access

    Prescribing cascades of antigout medications from thiazide diuretics in gout-naïve hypertensive adults receiving first-line pharmacological management

    Prescribing cascade is a significant clinical problem but is often overlooked. We explore the incidence of the prescribing cascades of antigout medications related to thiazide treatment in gout-naïve hypertens...

    Shang-Yeh Lu, Hsing-Yu Hsu, Yow-Wen Hsieh, Chiung-Ray Lu in Scientific Reports (2024)

  5. Article

    Open Access

    Cerebrospinal fluid shunt surgery reduces the risk of develo** dementia and Alzheimer’s disease in patients with idiopathic normal pressure hydrocephalus: a nationwide population-based propensity-weighted cohort study

    Patients with idiopathic normal-pressure hydrocephalus (iNPH) are predisposed to develo** dementing disorders. Cerebrospinal fluid (CSF) shunt implantation is a treatment used to improve the motor and cognit...

    Pao-Hui Tseng, Wan-Ting Huang, Jen-Hung Wang in Fluids and Barriers of the CNS (2024)

  6. No Access

    Chapter

    Contemporary Management of Pediatric Brainstem Tumors

    Brain tumors are the second most common malignancy in childhood. Around 15–20% of pediatric brain tumors occur in the brainstem. The most common type of brainstem tumor are diffuse tumors in the ventral pons, ...

    Sheng-Che Chou, Yu-Ning Chen, Hsin-Yi Huang in Advances and Technical Standards in Neuros… (2024)

  7. Article

    Open Access

    Role of the autonomic nervous system in young, middle-aged, and older individuals with essential hypertension and sleep-related changes in neurocardiac regulation

    Essential hypertension involves complex cardiovascular regulation. The autonomic nervous system function fluctuates throughout the sleep–wake cycle and changes with advancing age. However, the precise role of ...

    Chia-Hsin Yeh, Chun-Yu Chen, Yu-En Kuo, Chieh-Wen Chen in Scientific Reports (2023)

  8. No Access

    Article

    Use of calcium channel blockers and risk of breast cancer among women aged 55 years and older: a nationwide population-based cohort study

    This retrospective cohort study was aimed to compare the incidence of breast cancer among women aged ≥55 who received calcium channel blockers and angiotensin converting enzyme inhibitors/angiotensin II recept...

    Shin-Yi Lin, Hsin-Yi Huang, Liang-Ting Chiang, Ling-Ya Huang in Hypertension Research (2023)

  9. Article

    Open Access

    Histone deacetylase III interactions with BK polyomavirus large tumor antigen may affect protein stability

    Human polyomavirus BK (BKPyV) causes associated nephropathy and contributes to urinary tract cancer development in renal transplant recipients. Large tumor antigen (LT) is an early protein essential in the pol...

    Yueh-Han Hsu, Chun-Nun Chao, Hsin-Yi Huang, Pei-Wen Zhao, Pang-Hung Hsu in Virology Journal (2023)

  10. Article

    Open Access

    Rapid digital pathology of H&E-stained fresh human brain specimens as an alternative to frozen biopsy

    Hematoxylin and Eosin (H&E)-based frozen section (FS) pathology is presently the global standard for intraoperative tumor assessment (ITA). Preparation of frozen section is labor intensive, which might consume...

    Bhaskar Jyoti Borah, Yao-Chen Tseng, Kuo-Chuan Wang in Communications Medicine (2023)

  11. Article

    Open Access

    Mir125b-2 imprinted in human but not mouse brain regulates hippocampal function and circuit in mice

    Genomic imprinting predominantly occurs in the placenta and brain. Few imprinted microRNAs have been identified in the brain, and their functional roles in the brain are not clear. Here we show paternal, but n...

    Ming-Yi Chou, Xuhui Cao, Kuan-Chu Hou, Meng-Han Tsai, Chih-Yu Lee in Communications Biology (2023)

  12. No Access

    Chapter and Conference Paper

    Develo** an Emotional Interaction Design for Social Anxiety Disorders (SAD)

    This study focuses on using books in libraries as an interactive medium, aiming to help individuals with social anxiety disorder alleviate their anxiety and establish positive social experiences. The research ...

    HsiangTing Chien, Hsin-Yi Huang, Teng-Wen Chang in HCI International 2023 Posters (2023)

  13. Article

    Open Access

    Effects of age and sex on vasomotor activity and baroreflex sensitivity during the sleep–wake cycle

    Cardiovascular function is related to age, sex, and state of consciousness. We hypothesized that cardiovagal baroreflex sensitivity (BRS) demonstrates different patterns in both sexes before and after 50 years...

    Chia-Hsin Yeh, Terry B. J. Kuo, Jia-Yi Li, Kuan-Liang Kuo in Scientific Reports (2022)

  14. Article

    Open Access

    Association of advanced paternal age with lung function at school age

    Epidemiological studies suggest that advanced paternal age impact offspring health, but its impact on respiratory health is unclear. This study aimed to investigate the association of paternal age with lung fu...

    Chun-Chun Gau, Hsin-Ju Lee, Hung-Yi Lu, Chao-Yi Wu, Hsin-Yi Huang in Respiratory Research (2022)

  15. Article

    Open Access

    Unusually high incidence of polyomavirus JC infection in the higher grade of colorectal cancer tissues in Taiwan

    The human JC polyomavirus (JCPyV) has been detected in colorectal cancer (CRC) tissues and is suggested to contribute to CRC tumorigenesis. The rearrangement of the JCPyV regulatory region is supposedly associ...

    Chuan-Yin Fang, San-Yuan Chen, Bo-**u Hsiao in European Journal of Medical Research (2022)

  16. No Access

    Article

    Therapeutic targeting of the mevalonate–geranylgeranyl diphosphate pathway with statins overcomes chemotherapy resistance in small cell lung cancer

    Small cell lung cancer (SCLC) lacks effective treatments to overcome chemoresistance. Here we established multiple human chemoresistant xenograft models through long-term intermittent chemotherapy, mimicking c...

    Chenchen Guo, Ruijie Wan, Yayi He, Shu-Hai Lin, Jiayu Cao, Ying Qiu in Nature Cancer (2022)

  17. No Access

    Article

    ViDA: develo** a visualization system for a Design-Fabrication-Assembly (D-F-A) process

    Most designs, especially architecture and product design, involve the collective efforts of multiple disciplinary teams. These kinds of designs encounter many problems because of the need to implement various ...

    Teng-Wen Chang, Chun-Yen Chen, Hsin-Yi Huang in Multimedia Tools and Applications (2022)

  18. Article

    Open Access

    Allergic diseases attributable to atopy in a population sample of Asian children

    The proportion of allergic diseases attributable to atopy remains a subject of controversy. This study aimed to estimate the population risk of physician-diagnosed asthma, rhinitis and eczema attributed to ato...

    Chao-Yi Wu, Hsin-Yi Huang, Wen-Chi Pan, Sui-Ling Liao, Man-Chin Hua in Scientific Reports (2021)

  19. Article

    Open Access

    A systematic dissection of the epigenomic heterogeneity of lung adenocarcinoma reveals two different subclasses with distinct prognosis and core regulatory networks

    Lung adenocarcinoma (LUAD) is a highly malignant and heterogeneous tumor that involves various oncogenic genetic alterations. Epigenetic processes play important roles in lung cancer development. However, the ...

    Chongze Yuan, Haojie Chen, Shiqi Tu, Hsin-Yi Huang, Yunjian Pan in Genome Biology (2021)

  20. Chapter

    Correction to: CoFabs: An Interactive Fabrication Process Framework

    In the original version of the book, the following belated corrections have been made

    Teng-Wen Chang, Chi-Fu Hsiao, Chun-Yen Chen, Hsin-Yi Huang in Architectural Intelligence (2020)

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