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Article
Multi-task Chinese aspect-based sentiment analysis framework for service improvement: a case study on BNB reviews
User-generated content has become an essential factor influencing customer choice in the selection of hotel and bed and breakfast (BNB) accommodation. It is important for entrepreneurs to effectively analyze c...
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Article
Open AccessComparing transfusion reactions between pre-storage and post-storage leukoreduced apheresis platelets: an analysis using propensity score matching
Transfusion reactions induced by platelet transfusions may be reduced and alleviated by leukocyte reduction of platelets. Although leukoreduction of apheresis platelets can be performed either pre-storage or p...
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Article
Low-dose prasugrel versus standard-dose ticagrelor in east Asian patients with acute coronary syndrome
Low-dose prasugrel demonstrated a similar effectiveness profile to clopidogrel in East Asian ACS patients, but its comparison with another new-generation potent P2Y12 inhibitor, ticagrelor, remains unclear. To co...
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Article
Open AccessPrescribing cascades of antigout medications from thiazide diuretics in gout-naïve hypertensive adults receiving first-line pharmacological management
Prescribing cascade is a significant clinical problem but is often overlooked. We explore the incidence of the prescribing cascades of antigout medications related to thiazide treatment in gout-naïve hypertens...
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Article
Open AccessCerebrospinal fluid shunt surgery reduces the risk of develo** dementia and Alzheimer’s disease in patients with idiopathic normal pressure hydrocephalus: a nationwide population-based propensity-weighted cohort study
Patients with idiopathic normal-pressure hydrocephalus (iNPH) are predisposed to develo** dementing disorders. Cerebrospinal fluid (CSF) shunt implantation is a treatment used to improve the motor and cognit...
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Chapter
Contemporary Management of Pediatric Brainstem Tumors
Brain tumors are the second most common malignancy in childhood. Around 15–20% of pediatric brain tumors occur in the brainstem. The most common type of brainstem tumor are diffuse tumors in the ventral pons, ...
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Article
Open AccessRole of the autonomic nervous system in young, middle-aged, and older individuals with essential hypertension and sleep-related changes in neurocardiac regulation
Essential hypertension involves complex cardiovascular regulation. The autonomic nervous system function fluctuates throughout the sleep–wake cycle and changes with advancing age. However, the precise role of ...
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Article
Use of calcium channel blockers and risk of breast cancer among women aged 55 years and older: a nationwide population-based cohort study
This retrospective cohort study was aimed to compare the incidence of breast cancer among women aged ≥55 who received calcium channel blockers and angiotensin converting enzyme inhibitors/angiotensin II recept...
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Article
Open AccessHistone deacetylase III interactions with BK polyomavirus large tumor antigen may affect protein stability
Human polyomavirus BK (BKPyV) causes associated nephropathy and contributes to urinary tract cancer development in renal transplant recipients. Large tumor antigen (LT) is an early protein essential in the pol...
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Article
Open AccessRapid digital pathology of H&E-stained fresh human brain specimens as an alternative to frozen biopsy
Hematoxylin and Eosin (H&E)-based frozen section (FS) pathology is presently the global standard for intraoperative tumor assessment (ITA). Preparation of frozen section is labor intensive, which might consume...
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Article
Open AccessMir125b-2 imprinted in human but not mouse brain regulates hippocampal function and circuit in mice
Genomic imprinting predominantly occurs in the placenta and brain. Few imprinted microRNAs have been identified in the brain, and their functional roles in the brain are not clear. Here we show paternal, but n...
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Chapter and Conference Paper
Develo** an Emotional Interaction Design for Social Anxiety Disorders (SAD)
This study focuses on using books in libraries as an interactive medium, aiming to help individuals with social anxiety disorder alleviate their anxiety and establish positive social experiences. The research ...
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Article
Open AccessEffects of age and sex on vasomotor activity and baroreflex sensitivity during the sleep–wake cycle
Cardiovascular function is related to age, sex, and state of consciousness. We hypothesized that cardiovagal baroreflex sensitivity (BRS) demonstrates different patterns in both sexes before and after 50 years...
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Article
Open AccessAssociation of advanced paternal age with lung function at school age
Epidemiological studies suggest that advanced paternal age impact offspring health, but its impact on respiratory health is unclear. This study aimed to investigate the association of paternal age with lung fu...
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Article
Open AccessUnusually high incidence of polyomavirus JC infection in the higher grade of colorectal cancer tissues in Taiwan
The human JC polyomavirus (JCPyV) has been detected in colorectal cancer (CRC) tissues and is suggested to contribute to CRC tumorigenesis. The rearrangement of the JCPyV regulatory region is supposedly associ...
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Article
Therapeutic targeting of the mevalonate–geranylgeranyl diphosphate pathway with statins overcomes chemotherapy resistance in small cell lung cancer
Small cell lung cancer (SCLC) lacks effective treatments to overcome chemoresistance. Here we established multiple human chemoresistant xenograft models through long-term intermittent chemotherapy, mimicking c...
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Article
ViDA: develo** a visualization system for a Design-Fabrication-Assembly (D-F-A) process
Most designs, especially architecture and product design, involve the collective efforts of multiple disciplinary teams. These kinds of designs encounter many problems because of the need to implement various ...
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Article
Open AccessAllergic diseases attributable to atopy in a population sample of Asian children
The proportion of allergic diseases attributable to atopy remains a subject of controversy. This study aimed to estimate the population risk of physician-diagnosed asthma, rhinitis and eczema attributed to ato...
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Article
Open AccessA systematic dissection of the epigenomic heterogeneity of lung adenocarcinoma reveals two different subclasses with distinct prognosis and core regulatory networks
Lung adenocarcinoma (LUAD) is a highly malignant and heterogeneous tumor that involves various oncogenic genetic alterations. Epigenetic processes play important roles in lung cancer development. However, the ...
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Chapter
Correction to: CoFabs: An Interactive Fabrication Process Framework
In the original version of the book, the following belated corrections have been made