5 Result(s)

Article

Total-body imaging of mu-opioid receptors with [¹¹C]carfentanil in non-human primates

Mu-opioid receptors (MORs) are widely expressed in the central nervous system (CNS), peripheral organs, and immune system. This study measured the whole body distribution of MORs in rhesus macaques using the M...

Chia-Ju Hsieh, Catherine Hou, Hsiaoju Lee… in European Journal of Nuclear Medicine and M… (2024)

Article

Correction: [¹⁸F]ROStrace detects oxidative stress in vivo and predicts progression of Alzheimer’s disease pathology in APP/PS1 mice

Chia-Ju Hsieh, Catherine Hou, Yi Zhu, Ji Youn Lee, Neha Kohli… in EJNMMI Research (2023)

Article

[¹⁸F]ROStrace detects oxidative stress in vivo and predicts progression of Alzheimer’s disease pathology in APP/PS1 mice

Oxidative stress is implicated in the pathogenesis of the most common neurodegenerative diseases, such as Alzheimer’s disease (AD). However, tracking oxidative stress in the brain has proven difficult and impe...

Chia-Ju Hsieh, Catherine Hou, Yi Zhu, Ji Youn Lee, Neha Kohli… in EJNMMI Research (2022)

Article

Validation of gallbladder absorbed radiation dose reduction simulation: human dosimetry of [¹⁸F]fluortriopride

[¹⁸F]Fluortriopride (FTP) was developed as a dopamine D3-selective radiotracer, thought to be important to neurobiological reward pathways and implicated in drug addiction, Parkinson’s disease, and schizophrenia....

Robert K. Doot, Jacob G. Dubroff, Joshua S. Scheuermann, Kyle J. Labban… in EJNMMI Physics (2018)

Article

Automation of the Radiosynthesis of Six Different ¹⁸F-labeled radiotracers on the AllinOne

Fast implementation of positron emission tomography (PET) into clinical and preclinical studies highly demands automated synthesis for the preparation of PET radiopharmaceuticals in a safe and reproducible man...

Shihong Li, Alexander Schmitz, Hsiaoju Lee… in EJNMMI Radiopharmacy and Chemistry (2016)