![Loading...](https://link.springer.com/static/c4a417b97a76cc2980e3c25e2271af3129e08bbe/images/pdf-preview/spacer.gif)
-
Article
Open AccessBacPE: a versatile prime-editing platform in bacteria by inhibiting DNA exonucleases
Prime editing allows precise installation of any single base substitution and small insertions and deletions without requiring homologous recombination or double-strand DNA breaks in eukaryotic cells. However,...
-
Article
Open AccessFOXI3 pathogenic variants cause one form of craniofacial microsomia
Craniofacial microsomia (CFM; also known as Goldenhar syndrome), is a craniofacial developmental disorder of variable expressivity and severity with a recognizable set of abnormalities. These birth defects are...
-
Article
Open AccessMolecularly self‐fueled nano-penetrator for nonpharmaceutical treatment of thrombosis and ischemic stroke
Thrombotic cerebro-cardiovascular diseases are the leading causes of disability and death worldwide. However, current drug therapeutics are compromised by narrow therapeutic windows, unsatisfactory thrombolysi...
-
Article
Open AccessSelective light absorber-assisted single nickel atom catalysts for ambient sunlight-driven CO2 methanation
Ambient sunlight-driven CO2 methanation cannot be realized due to the temperature being less than 80 °C upon irradiation with dispersed solar energy. In this work, a selective light absorber was used to construct...
-
Article
Open AccessThe mitochondrial genome map of Nelumbo nucifera reveals ancient evolutionary features
Nelumbo nucifera is an evolutionary relic from the Late Cretaceous period. Sequencing the N. nucifera mitochondrial genome is important for elucidating the evolutionary characteristics of basal eudicots. Here, th...
-
Article
Opening of the Tethys in southwest China and its significance to the breakup of East Gondwanaland in late Paleozoic: Evidence from SHRIMP U-Pb zircon analyses for the Garzê ophiolite block
SHRIMP U-Pb zircon analyses for a gabbro sample from the Garzê ophiolite block yielded a mean206Pb/238U age of 292 ±4 Ma, which indicated that the spreading time of the Garzê-Litang Tethys was most likely at the ...