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  1. Article

    Open Access

    BacPE: a versatile prime-editing platform in bacteria by inhibiting DNA exonucleases

    Prime editing allows precise installation of any single base substitution and small insertions and deletions without requiring homologous recombination or double-strand DNA breaks in eukaryotic cells. However,...

    Hongyuan Zhang, Jiacheng Ma, Zhaowei Wu, **aoyang Chen in Nature Communications (2024)

  2. Article

    Open Access

    FOXI3 pathogenic variants cause one form of craniofacial microsomia

    Craniofacial microsomia (CFM; also known as Goldenhar syndrome), is a craniofacial developmental disorder of variable expressivity and severity with a recognizable set of abnormalities. These birth defects are...

    Ke Mao, Christelle Borel, Muhammad Ansar, Angad Jolly in Nature Communications (2023)

  3. Article

    Open Access

    Molecularly self‐fueled nano-penetrator for nonpharmaceutical treatment of thrombosis and ischemic stroke

    Thrombotic cerebro-cardiovascular diseases are the leading causes of disability and death worldwide. However, current drug therapeutics are compromised by narrow therapeutic windows, unsatisfactory thrombolysi...

    Hongyuan Zhang, Zhiqiang Zhao, Shengnan Sun, Sen Zhang in Nature Communications (2023)

  4. Article

    Open Access

    Selective light absorber-assisted single nickel atom catalysts for ambient sunlight-driven CO2 methanation

    Ambient sunlight-driven CO2 methanation cannot be realized due to the temperature being less than 80 °C upon irradiation with dispersed solar energy. In this work, a selective light absorber was used to construct...

    Yaguang Li, Jianchao Hao, Hui Song, Fengyu Zhang, **anhua Bai in Nature Communications (2019)

  5. Article

    Open Access

    The mitochondrial genome map of Nelumbo nucifera reveals ancient evolutionary features

    Nelumbo nucifera is an evolutionary relic from the Late Cretaceous period. Sequencing the N. nucifera mitochondrial genome is important for elucidating the evolutionary characteristics of basal eudicots. Here, th...

    Songtao Gui, Zhihua Wu, Hongyuan Zhang, Yinzhen Zheng, Zhixuan Zhu in Scientific Reports (2016)

  6. No Access

    Article

    Opening of the Tethys in southwest China and its significance to the breakup of East Gondwanaland in late Paleozoic: Evidence from SHRIMP U-Pb zircon analyses for the Garzê ophiolite block

    SHRIMP U-Pb zircon analyses for a gabbro sample from the Garzê ophiolite block yielded a mean206Pb/238U age of 292 ±4 Ma, which indicated that the spreading time of the Garzê-Litang Tethys was most likely at the ...

    Quanren Yan, Zongqi Wang, Shuwen Liu, Qiugen Li, Hongyuan Zhang in Chinese Science Bulletin (2005)