-
Article
Open AccessSimultaneous detection of dental caries and fissure sealant in intraoral photos by deep learning: a pilot study
Deep learning, as an artificial intelligence method has been proved to be powerful in analyzing images. The purpose of this study is to construct a deep learning-based model (ToothNet) for the simultaneous det...
-
Article
Discovery of Novel Anthranilic Diamide Derivatives Bearing Sulfoximine Group as Potent Insecticide Candidates
The fall armyworm, Spodoptera frugiperda (S. frugiperda), represents the most resistant insect species and poses serious threat to grain yield. Chlorantraniliprole (CHL), which targets the ryanodine receptors (Ry...
-
Article
Open AccessBacPE: a versatile prime-editing platform in bacteria by inhibiting DNA exonucleases
Prime editing allows precise installation of any single base substitution and small insertions and deletions without requiring homologous recombination or double-strand DNA breaks in eukaryotic cells. However,...
-
Article
Open AccessThe effect of albumin and hemoglobin levels on the prognosis of early-stage cervical cancer: a prospective, single-center–based cohort study
Serum albumin (ALB) and hemoglobin (HGB) are important serum biochemical indices of the nutritional status of patients and are associated with cancer development. We investigated the relationship between ALB a...
-
Article
Open AccessWeighted gene co-expression network analysis identified hub genes critical to fatty acid composition in Gushi chicken breast muscle
The composition and content of fatty acids in the breast muscle are important factors influencing meat quality. In this study, we investigated the fatty acid composition and content in the breast muscle of Gus...
-
Article
Open AccessThe typical polypoid adenomyoma is a special form of endometrial polyp: a case-controlled study with a large sample size
To investigate clinicopathological differences between typical endometrial polypoid adenomyomas (TPAs) and endometrial polyps (EPs) and to determine the risk factors and recurrence of TPA and further clarify t...
-
Article
Open AccessGenetic architecture and key regulatory genes of fatty acid composition in Gushi chicken breast muscle determined by GWAS and WGCNA
Fatty acids composition in poultry muscle is directly related to its tenderness, flavour, and juiciness, whereas its genetic mechanisms have not been elucidated. In this study, the genetic structure and key re...
-
Article
Open AccessTranscriptome analysis reveals FABP5 as a key player in the development of chicken abdominal fat, regulated by miR-122-5p targeting
The development of abdominal fat and meat quality are closely related and can impact economic efficiency. In this study, we conducted transcriptome sequencing of the abdominal fat tissue of Gushi chickens at 6...
-
Article
Open AccessFOXI3 pathogenic variants cause one form of craniofacial microsomia
Craniofacial microsomia (CFM; also known as Goldenhar syndrome), is a craniofacial developmental disorder of variable expressivity and severity with a recognizable set of abnormalities. These birth defects are...
-
Article
Open AccessMolecularly self‐fueled nano-penetrator for nonpharmaceutical treatment of thrombosis and ischemic stroke
Thrombotic cerebro-cardiovascular diseases are the leading causes of disability and death worldwide. However, current drug therapeutics are compromised by narrow therapeutic windows, unsatisfactory thrombolysi...
-
Article
Solving Elliptic Equations with Brownian Motion: Bias Reduction and Temporal Difference Learning
The Feynman-Kac formula provides a way to understand solutions to elliptic partial differential equations in terms of expectations of continuous time Markov processes. This connection allows for the creation o...
-
Article
Open AccessEvaluation of abdominal compression–decompression combined with chest compression CPR performed by a new device: Is the prognosis improved after this combination CPR technique?
This study was designed to compare the outcomes of standard cardiopulmonary resuscitation (STD-CPR) and combined chest compression and abdominal compression–decompression cardiopulmonary resuscitation (CO-CPR)...
-
Article
Multicomponent Effects on the Supercritical CO2 Systems: Mixture Critical Point and Phase Separation
Semi-closed supercritical CO2 (sCO2) gas turbine is a promising candidate for the next generation power cycles with high efficiency and almost 100% carbon capture. In this study, the multicomponent effects on the...
-
Chapter and Conference Paper
Reliable Transport Mechanism Based on Multi-queue Scheduling
In the Integrated Space and Onboard Network, transmission demands arrive randomly. In addition, the routing algorithm calculate the end-to-end paths the average occupied bandwidth over a period of time, causin...
-
Article
Complete genome sequence of a novel mitovirus associated with Lagenaria siceraria
Here, we report the discovery and molecular characterization of a novel mitovirus isolated from tissues of Lagenaria siceraria, named "Lagenaria siceraria associated mitovirus 1" (LsaMV1). Next-generation sequenc...
-
Article
Open AccessMutant IDH and non-mutant chondrosarcomas display distinct cellular metabolomes
Majority of chondrosarcomas are associated with a number of genetic alterations, including somatic mutations in isocitrate dehydrogenase 1 (IDH1) and IDH2 genes, but the downstream effects of these mutated enzyme...
-
Article
Enchondromatosis and Growth Plate Development
Enchondroma is a common cartilage benign tumor that develops from dysregulation of chondrocyte terminal differentiation during growth plate development. Here we provide an overview of recent progress in unders...
-
Article
Catalytic-state structure and engineering of Streptococcus thermophilus Cas9
Cas9 nucleases recognize and cleave their target DNA through base pairing of a guide RNA with a spacer adjacent to a protospacer adjacent motif (PAM). Streptococcus thermophilus Cas9 (St1Cas9), a smaller Cas9 ort...
-
Article
Decorating carbon felt with oxides by dip** as dendrite-free host for lithium metal anode
Although 3D frameworks as collectors have been proved to improve the electrochemical performance of lithium metal anodes, the development of lithiophilic frameworks to form a compact anode is still desired. He...
-
Chapter and Conference Paper
Bistatic SAR Imaging Based on Compressive Sensing Approach
The compressive sensing (CS) technique has been introduced to the field of synthetic aperture radar (SAR) imaging procedure to reduce the amount of measurements. In this letter, a novel algorithm for bistatic ...
