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Open AccessAn optimal combination of four active components in Huangqin decoction for the synergistic sensitization of irinotecan against colorectal cancer
Irinotecan (CPT-11) is a first-line treatment for advanced colorectal cancer (CRC). Four components (baicalin, baicalein, wogonin, and glycyrrhizic acid) derived from Huangqin Decoction (HQD) have been proven ...
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Article
Open AccessCYP2E1 deficit mediates cholic acid-induced malignant growth in hepatocellular carcinoma cells
Increased level of serum cholic acid (CA) is often accompanied with decreased CYP2E1 expression in hepatocellular carcinoma (HCC) patients. However, the roles of CA and CYP2E1 in hepatocarcinogenesis have not ...
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Article
Configuration paths to high-value patents: evidence from patents winning the China Patent Awards
Firms are seeking effective ways to cultivate high-value patents to support the goals of their innovative development, which has raised a promising research issue on different paths to high-value patents. Howe...
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Article
Role of Oxidative Stress in the Occurrence and Development of Cognitive Dysfunction in Patients with Obstructive Sleep Apnea Syndrome
Obstructive sleep apnea syndrome (OSAS) causes recurrent apnea and intermittent hypoxia at night, leading to several complications such as cognitive dysfunction. However, the molecular mechanisms underlying co...
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Article
The Role of PKM2 in Multiple Signaling Pathways Related to Neurological Diseases
Pyruvate kinase M2 (PKM2) is a key rate-limiting enzyme in glycolysis. It is well known that PKM2 plays a vital role in the proliferation of tumor cells. However, PKM2 can also exert its biological functions b...
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Article
An anti-wear tool structure with integrated-micro hybrid cutting edges for milling of carbon fiber–reinforced plastics composites
In the milling of CFRP, the most widely used cemented carbide tool is vulnerable to severe wear. Focusing on the issue, the study aims to reduce the tool wear extent by the way of designing high-performance to...
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Article
Integrated metabolomics and transcriptomics analyses reveal the key genes regulating differential metabolites of longissimus dorsi muscle in castrated South Sichuan black goats (Capra hircus)
The main aim of the current work was to explore the differential metabolites and differentially expressed genes of longissimus dorsi muscle (LDM) between castrated and uncastrated fattening male South Sichuan ...
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Article
Research on the Relationship between Surface Defects and Preparation Quality Evaluation of Ni-Based Single Crystal Alloy
The preparation quality of Ni-based single crystal alloy (NSCA) can be qualitatively reflected based on its surface defects. However, the quantitative expression of the preparation quality of NSCA is difficult...
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Article
Adsorption performance and mechanism of chromium on β-cyclodextrin-modified molybdenum disulfide
In recent years, many heavy metal ions have been discharged into the environment, which is threatening human health. Herein, the β-cyclodextrin-modified molybdenum disulfide composite (β-CD/MoS2) was prepared to ...
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Article
Spectroscopic investigation of novel yellow-emitting Li3Bi3Te2O12:Dy3+ phosphors with high thermal stability for w-LEDs applications
A series of Li3Bi3Te2O12:xDy3+ (x = 0.01, 0.02, 0.05, 0.10, 0.15, 0.20, and 0.30 mol) samples were successfully prepared by high-temperature sintering method. The phase purities of the Li3Bi3Te2O12:Dy3+ phosphors...
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Article
Construction of an egg-like DTAB/SiO2 composite for the enhanced removal of uranium
For the past few years, the environmental safety problems of radioactive nuclides caused wide public concern. In this work, the dodecyl trimethyl ammonium bromide-modified silicon dioxide composite (DTAB/SiO2) wa...
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Research of dual-ion polymer batteries based on N-butyl-N-methylpiperidinium bis(trifluoromethylsulfonyl)imide ionic liquid electrolyte
The development of dual-ion metal-free batteries is restricted by the strong self-discharge effect and dissolution of some anode active materials in the polar electrolyte. This in turn leads to low coulombic e...
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Article
Quantitative assessment of normal hip cartilage in children under 9 years old by T2 map**
To investigate the variation in T2 at different zones of normal hip cartilage in children and the relationship between T2 value and age.
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Article
Open AccessIntrusion detection system combined enhanced random forest with SMOTE algorithm
Network security is subject to malicious attacks from multiple sources, and intrusion detection systems play a key role in maintaining network security. During the training of intrusion detection models, the d...
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Article
Open AccessPrevalence of preoperative Deep Venous Thrombosis (DVT) following elderly intertrochanteric fractures and development of a risk prediction model
This study aimed to investigate the prevalence of preoperative deep venous thrombosis (DVT) following intertrochanteric fractures in the elderly and identify the associated factors, based on which a risk predi...
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RETRACTED ARTICLE: Wearable IoT based cloud assisted framework for swimming persons in health monitoring system
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Sulfur-induced porous carbon nanofibers composite SiO as bifunctional anode for high-performance Li-ion storage
Non-conductivity and volume expansion are the main factors hindering the development of SiO anode materials. To solve these problems, in this work, a bifunctional anode was prepared with sulfur-induced SiO emb...
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Article
Experimental Study on Photocatalytic Treatment of Alien Organisms in Ship Ballast Water by F/Ce–TiO2
A large number of microorganisms and pathogens are carried in the ballast water of ships. With the navigation and discharge of foreign countries, harmful organisms in the ballast water are brought into the wor...
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Open AccessEffects of 45S5 bioactive glass on the remineralization of early carious lesions in deciduous teeth: an in vitro study
Early childhood caries has been designated as a serious public health problem. The traditional restoration method is very challenging, especially in uncooperative patients. Non-invasive therapy, like remineral...
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Article
ZnO/TiO2/C nanofibers by electrospinning for high-performance lithium storage
Long cyclic stability and high rate performance have been the major challenges of lithium-ion batteries (LIBs). Composite metal oxides as a promising anode materials for LIBs have been studied extensively due ...