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  1. Article

    Open Access

    Quinic acid regulated TMA/TMAO-related lipid metabolism and vascular endothelial function through gut microbiota to inhibit atherosclerotic

    Quinic acid (QA) and its derivatives have good lipid-lowering and hepatoprotective functions, but their role in atherosclerosis remains unknown. This study attempted to investigate the mechanism of QA on ather...

    Qiao **, Chiyuan Zhang, Ran Chen, Lu** Jiang in Journal of Translational Medicine (2024)

  2. Article

    Open Access

    Chemotherapy re-use versus anti-angiogenic monotherapy as the third-line treatment of patients with metastatic colorectal cancer: a real-world cohort study

    There are various recommendations for third-line treatment in mCRC, however, there is no consensus on who is more suitable for particular strategy. Chemotherapy re-use in third-line setting is a common option ...

    **g**g Duan, Lila Zhu, Yinghui Shi, Weixue Wang, Tongtong Wang, Tao Ning in BMC Cancer (2024)

  3. Article

    Open Access

    Combined score based on plasma fibrinogen and platelet-lymphocyte ratio as a prognostic biomarker in esophageal squamous cell carcinoma

    Increasing evidence has showed that inflammatory biomarkers, including neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR) and fibrinogen can be used as predictors in the prognosis of esop...

    Yuchong Yang, Hui Tan, Yao Lu, Jipeng Mei, Mengqi Zhang, Ming Bai, **a Wang in BMC Cancer (2024)

  4. Article

    Retraction Note: Exosome circRNA secreted from adipocytes promotes the growth of hepatocellular carcinoma by targeting deubiquitination-related USP7

    Haiyang Zhang, Ting Deng, Shaohua Ge, Ying Liu, Ming Bai, Kegan Zhu, Qian Fan in Oncogene (2023)

  5. Article

    Open Access

    The optimal time of starting adjuvant chemotherapy after curative surgery in patients with colorectal cancer

    Postoperative adjuvant chemotherapy (AC) is now well-accepted as standard for high-risk stage II and stage III colorectal cancer (CRC) patients, however the optimal time to initiate AC remains elusive.

    Yuchong Yang, Yao Lu, Hui Tan, Ming Bai, **a Wang, Shaohua Ge, Tao Ning in BMC Cancer (2023)

  6. Article

    Open Access

    Anti-Alzheimers molecular mechanism of icariin: insights from gut microbiota, metabolomics, and network pharmacology

    Icariin (ICA), an active ingredient extracted from Epimedium species, has shown promising results in the treatment of Alzheimer's disease (AD), although its potential therapeutic mechanism remains largely unknown...

    Yuqing Liu, Hongli Li, **aowei Wang, Jianhua Huang in Journal of Translational Medicine (2023)

  7. Article

    Open Access

    Sintilimab Plus Apatinib and Chemotherapy as Second‑/Third-Line treatment for Advanced Gastric or Gastroesophageal Junction Adenocarcinoma: a prospective, Single-Arm, phase II trial

    The prognosis of patients with previously treated advanced gastric or gastroesophageal junction (GEJ) cancer remains poor. Given the robust development of immunotherapy and targeted therapy during the last dec...

    Le Zhang, Weixue Wang, Shaohua Ge, Hongli Li, Ming Bai, **g**g Duan in BMC Cancer (2023)

  8. Article

    Open Access

    The prognosis of different types of pleural tags based on radiologic-pathologic comparison

    There are increasing numbers of studies of pleural tags (PTs). The purpose of this case series was to classify the PTs in patients with peripheral pulmonary adenocarcinoma based on radiologic-pathologic compar...

    Yao Meng, Jie Gao, Chongchong Wu, Mei **e, **dong Ma, Xuelei Zang in BMC Cancer (2022)

  9. No Access

    Article

    The HSF1/miR-135b-5p axis induces protective autophagy to promote oxaliplatin resistance through the MUL1/ULK1 pathway in colorectal cancer

    Oxaliplatin (oxa) is widely used in the treatment of colorectal cancer (CRC), but the development of oxaliplatin resistance is a major obstacle to the therapeutic efficacy in patients. MicroRNAs (miRNAs), endo...

    Huiya Wang, **a Wang, Haiyang Zhang, Ting Deng, Rui Liu, Ying Liu, Hongli Li in Oncogene (2021)

  10. Article

    Open Access

    Blocking Msr1 by berberine alkaloids inhibits caspase-11-dependent coagulation in bacterial sepsis

    Chuang Yuan, Ming Wu, Qicai **ao, Wang Zhao in Signal Transduction and Targeted Therapy (2021)

  11. Article

    Open Access

    Clinical use of tumor biomarkers in prediction for prognosis and chemotherapeutic effect in esophageal squamous cell carcinoma

    Growing evidence has indicated that tumor biomarkers, including cytokeratin 19 fragment antigen 21–1 (Cyfra21–1), carbohydrate antigen 19–9 (CA19–9), carbohydrate antigen 72–4 (CA72–4), carcinoembryonic antige...

    Yuchong Yang, Xuanzhang Huang, Likun Zhou, Ting Deng, Tao Ning, Rui Liu in BMC Cancer (2019)

  12. Article

    Open Access

    RETRACTED ARTICLE: Exosome circRNA secreted from adipocytes promotes the growth of hepatocellular carcinoma by targeting deubiquitination-related USP7

    Hepatocellular carcinoma (HCC), the major form of liver cancer, has shown increasing incidence and poor prognosis. Adipose tissue is known to function in energy storage and metabolism regulation by the secreti...

    Haiyang Zhang, Ting Deng, Shaohua Ge, Ying Liu, Ming Bai, Kegan Zhu, Qian Fan in Oncogene (2019)

  13. Article

    Open Access

    Liuzijue Qigong vs traditional breathing training for patients with post-stroke dysarthria complicated with abnormal respiratory control: study protocol of a single center randomized controlled trial

    Stroke-induced dysarthria is caused by muscle weakness, sacral or muscular dystonia, and incoordination of the articulatory organ formed by organic lesions caused by cerebral vascular obstruction or sudden bur...

    Hongli Li, Gaiyan Li, Gongliang Liu, Ying Zhang in Trials (2018)