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1,606 Result(s)
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Article
Fleagrass (Adenosma buchneroides Bonati) Acts as a Fungicide Against Candida albicans by Damaging Its Cell Wall
Fleagrass, a herb known for its pleasant aroma, is widely used as a mosquito repellent, antibacterial agent, and for treating colds, reducing swelling, and alleviating pain. The antifungal effects of the essen...
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Sobolev Estimates for Singular-Degenerate Quasilinear Equations Beyond the \(A_2\) Class
We study a conormal boundary value problem for a class of quasilinear elliptic equations in bounded domain \(\Omega \) ...
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Experimental Investigation of Composite Formation Flying Using Disturbance-Free Payloads
Precise formation control is increasingly demanded in high-resolution remote sensing formations, gravitational detection interferometers and distributed space telescopes. One composite formation flying method ...
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High hyperdiploid karyotype with ≥ 49 chromosomes represents a heterogeneous subgroup of acute myeloid leukemia with differential TP53 mutation status and prognosis: a single-center study from China
High hyperdiploid karyotype with ≥ 49 chromosomes (which will be referred to as HHK) is rare in acute myeloid leukemia (AML). The European leukemia network (ELN) excluded those harboring only numerical changes...
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Disentangling the relationships of body mass index and circulating sex hormone concentrations in mammographic density using Mendelian randomization
Mammographic density phenotypes, adjusted for age and body mass index (BMI), are strong predictors of breast cancer risk. BMI is associated with mammographic density measures, but the role of circulating sex h...
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Open AccessPost-sepsis psychiatric disorder: Pathophysiology, prevention, and treatment
Post-sepsis psychiatric disorder, encompassing anxiety, depression, post-traumatic stress disorder and delirium, is a highly prevalent complication secondary to sepsis, resulting in a marked increase in long-t...
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Interleukin-19 in Bone Marrow Contributes to Bone Loss Via Suppressing Osteogenic Differentiation Potential of BMSCs in Old Mice
Cellular senescence is an important process related to the pathogenic mechanism of different disorders, especially bone loss. During senescence, bone marrow stromal cells (BMSCs) lose their self-renewal and fu...
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Dynamics of measles immunity from birth and following vaccination
Measles remains a major threat to human health despite widespread vaccination. While we know that maternal antibodies can impair vaccine-induced immunity, the relative contributions of pre-existing immunity le...
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Open AccessCTCF mutation at R567 causes developmental disorders via 3D genome rearrangement and abnormal neurodevelopment
The three-dimensional genome structure organized by CTCF is required for development. Clinically identified mutations in CTCF have been linked to adverse developmental outcomes. Nevertheless, the underlying mecha...
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Gold nanomaterials: important vectors in biosensing of breast cancer biomarkers
Breast cancer (BC) is one of the most common malignant tumors in women worldwide, and its incidence is increasing every year. Early diagnosis and treatment are critical to improve the curability and prognosis ...
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Open AccessUSP38 exacerbates pressure overload-induced left ventricular electrical remodeling
Ubiquitin-specific protease 38 (USP38), belonging to the USP family, is recognized for its role in controlling protein degradation and diverse biological processes. Ventricular arrhythmias (VAs) following hear...
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Open AccessAuthor Correction: TGF-β1/IL-11/MEK/ERK signaling mediates senescence-associated pulmonary fibrosis in a stress-induced premature senescence model of Bmi-1 deficiency
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Open AccessEffect of different lumbar–iliac fixation and sacral slope for Tile C1.3 pelvic fractures: a biomechanical study
Lumbar–iliac fixation (LIF) is a common treatment for Tile C1.3 pelvic fractures, but different techniques, including L4–L5/L5 unilateral LIF (L4–L5/L5 ULIF), bilateral LIF (BLIF), and L4–L5/L5 triangular oste...
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Open AccessTNIP3 protects against pathological cardiac hypertrophy by stabilizing STAT1
Pathological cardiac hypertrophy is one of the major risk factors of heart failure and other cardiovascular diseases. However, the mechanisms underlying pathological cardiac hypertrophy remain largely unknown....
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Open AccessGroin pain aggravated in short term contracted by COVID-19 in THA patients: a case-crossover study
The coronavirus disease 2019 (COVID-19) rapidly spreads worldwide and causes more suffering. The relation about the aggravation of inguinal pain and COVID-19 was unclear in patients with total hip arthroplasty...
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Open AccessAssessment of cerebrovascular alterations induced by inflammatory response and oxidative–nitrative stress after traumatic intracranial hypertension and a potential mitigation strategy
The rapid perfusion of cerebral arteries leads to a significant increase in intracranial blood volume, exposing patients with traumatic brain injury to the risk of diffuse brain swelling or malignant brain her...
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A modified method for isolating sinoatrial node myocytes from adult mice
Sinoatrial node (SAN) is the pacemaker of the heart in charge of initiating spontaneous electronical activity and controlling heart rate. Myocytes from SAN can generate spontaneous rhythmic action potentials, ...
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The Protective Role of Transcript-Induced in Spermiogenesis 40 in Cerebral Ischemia–Reperfusion Injury
Prompt reperfusion after cerebral ischemia is important to maintain neuronal survival and reduce permanent disability and death. However, the resupply of blood can induce oxidative stress, inflammatory respons...
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Open AccessA deep learning framework for predicting disease-gene associations with functional modules and graph augmentation
The exploration of gene-disease associations is crucial for understanding the mechanisms underlying disease onset and progression, with significant implications for prevention and treatment strategies. Advance...
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Open AccessMolecular transmission network analysis of newly diagnosed HIV-1 infections in Nan**g from 2019 to 2021
The objective of this study was to conduct a comprehensive analysis of the molecular transmission networks and transmitted drug resistance (TDR) patterns among individuals newly diagnosed with HIV-1 in Nan**g.