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Article
High nitrogen inhibits photosynthetic performance in a shade-tolerant and N-sensitive species Panax notoginseng
Nitrogen (N) is a primary factor limiting leaf photosynthesis. However, the mechanism of high-N-driven inhibition on photosynthetic efficiency and photoprotection is still unclear in the shade-tolerant and N-s...
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Article
Open AccessRaloxifene inhibits adipose tissue inflammation and adipogenesis through Wnt regulation in ovariectomized rats and 3 T3-L1 cells
Loss of ovarian function, as in menopause or after ovariectomy (OVX), is closely associated with obesity and white adipose tissue (WAT) inflammation. Estrogen replacement protects against postmenopausal obesit...
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Article
Development of a novel bacterial surface display system using truncated OmpT as an anchoring motif
An efficient bacterial surface display system based on the anchoring motif derived from Escherichia coli (E. coli) outer membrane protease OmpT was developed in this study.
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Article
Primary culture of lung fibroblasts from hyperoxia-exposed rats and a proliferative characteristics study
Lung fibrosis is an ultimate consequence of bronchopulmonary dysplasia (BPD) which shows the excessive proliferation of lung fibroblasts (LFs). To find a better model for studying the role of LFs in hyperoxia-...
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Article
5-aza-2′-deoxycytidine, a DNA methylation inhibitor, attenuates hyperoxia-induced lung fibrosis via re-expression of P16 in neonatal rats
P16 methylation plays an important role in the pathogenesis of hyperoxia-induced lung fibrosis. 5-aza-2′-deoxycytidine (5-aza-CdR) is a major methyltransferase-specific inhibitor. In this study, the effects of...
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Article
Open AccessCorrection: Corrigendum: A load of mice to hypergravity causes AMPKα repression with liver injury, which is overcome by preconditioning loads via Nrf2
Scientific Reports 5: Article number: 15643; published online: 23 October 2015; updated: 05 October 2016
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Article
Open AccessA load of mice to hypergravity causes AMPKα repression with liver injury, which is overcome by preconditioning loads via Nrf2
An understanding of the effects of hypergravity on energy homeostasis is necessary in managing proper physiological countermeasures for aerospace missions. This study investigated whether a single or multiple ...
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Article
Autophagy regulates hyperoxia-induced intracellular accumulation of surfactant protein C in alveolar type II cells
Surfactant protein C (SP-C) deficiency is a risk factor for hyperoxia-induced bronchopulmonary dysplasia in newborn infants. However, the role of SP-C deficiency in the process is unclear. Here, using neonatal...
