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Article
Identification and validation of ferroptosis-related genes for chronic rhinosinusitis with nasal polyps
Even though the great progress in the field of chronic rhinosinusitis with nasal polyps (CRSwNP) has been achieved, ferroptosis and its molecular mechanism in CRSwNP remain blank. We are the first to study the...
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Article
A comparison of the survival between laser surgery and radiation in T1aN0M0 glottic cancer: a population-based analysis and meta-analysis
The objective of this study is to compare the overall survival (OS) and the cancer-specific survival (CSS) for patients of T1aN0M0 glottic cancer who underwent laser surgery (LS) or radiation (RT).
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Article
Open AccessCharacteristics of recovered COVID-19 patients with recurrent positive RT-PCR findings in Wuhan, China: a retrospective study
Two months after the outbreak of coronavirus disease 2019 (COVID-19) in Wuhan, China, tens of thousands of hospitalized patients had recovered, and little is known about the follow-up of the recovered patients.
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Article
Open AccessHaimufang decoction, a Chinese medicine formula for lung cancer, arrests cell cycle, stimulates apoptosis in NCI-H1975 cells, and induces M1 polarization in RAW 264.7 macrophage cells
Lung cancer has the highest morbidity and mortality in the world and novel treatment strategies are still needed. Haimufang decoction (HMF) is a patented clinical prescription of traditional Chinese medicine f...
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Article
Open AccessDietary Sargassum fusiforme improves memory and reduces amyloid plaque load in an Alzheimer’s disease mouse model
Activation of liver X receptors (LXRs) by synthetic agonists was found to improve cognition in Alzheimer’s disease (AD) mice. However, these LXR agonists induce hypertriglyceridemia and hepatic steatosis, hamp...
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Article
Open AccessComprehensive comparison of polysaccharides from Ganoderma lucidum and G. sinense: chemical, antitumor, immunomodulating and gut-microbiota modulatory properties
Both Ganoderma lucidum (GL) and G. sinense (GS) are used as Lingzhi in China. Their functions are assumed to mainly derive from triterpenes and polysaccharides; however, the two species have very different triter...
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Article
Open AccessPRC1 contributes to tumorigenesis of lung adenocarcinoma in association with the Wnt/β-catenin signaling pathway
Protein regulator of cytokinesis-1 (PRC1) belongs to the microtubule-associated proteins (MAPs) family, and is involved in cytokinesis. Recent investigations suggest PRC1 involvement in human carcinogenesis, i...
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Article
Open AccessRapid development of metastatic pulmonary calcifications in primary hyperparathyroidism: a case report and literature review
Metastatic pulmonary calcification (MPC) is rarely reported in primary hyperparathyroidism, especially MPC develops quickly. We report such a case here with a literature review.
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Article
Predictive and prognostic significance of circulating endothelial cells in advanced non-small cell lung cancer patients
The aim of this study was to evaluate the predictive and prognostic values of circulating endothelial cells (CECs) in patients with advanced non-small cell lung cancer (NSCLC). A total of 102 newly diagnosed a...
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Article
Effect of Aging Treatment on Precipitation Behavior and Mechanical Properties of a Novel Aluminum–Lithium Alloy
In this work, the microstructure and precipitation phases were primarily characterized by transmission electron microscopy. The mechanical properties were evaluated by tensile and tear test. The results indic...
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Article
Chemical Constituents of Aglaia abbreviata
Chemical investigation of a Chinese indigenous Aglaia species, A. abbreviata, yielded a new 3,4-secodammarane triterpenoid (1), the known triterpenoids 2–9, the known flavaglines 10 and 11, and the known amide de...
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Article
Open AccessPrognostic value of secreted phosphoprotein-1 in pleural effusion associated with non-small cell lung cancer
Malignant pleural effusion (MPE) is a common complication of advanced lung cancer. Research has shown that secreted phosphoprotein-1 (SPP1) is essential in MPE associated with lung cancer. This retrospective s...
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Article
Association between the −1438G/A and T102C polymorphisms of 5-HT2A receptor gene and obstructive sleep apnea: a meta-analysis
The serotonin 2A (5-HT2A) receptor has been implicated in obstructive sleep apnea (OSA). Single nucleotide polymorphisms (SNPs) in the 5-HT2A gene have been found in OSA, the most common being −1438G/A and T10...
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Article
Chemotherapy plus multitargeted antiangiogenic tyrosine kinase inhibitors or chemotherapy alone in advanced NSCLC: a meta-analysis of randomized controlled trials
Most patients with advanced non-small-cell lung cancer (NSCLC) require systemic chemotherapy. Chemotherapy plus multitargeted antiangiogenic tyrosine kinase inhibitors (TKI; e.g., sorafenib, sunitinib, cediran...
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Article
Baseline and decline of serum ADAM28 during chemotherapy of advanced non-small cell lung cancer: a probable predictive and prognostic factor
ADAM28 (a disintegrin and metalloproteinase 28) is over-expressed in non-small cell lung cancer (NSCLC) with correlation to cancer proliferation, tumor size and lymph node metastasis. In the present study, we ...
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Article
The impact of E-cadherin expression on non-small cell lung cancer survival: a meta-analysis
E-cadherin has been implicated in invasiveness and metastasis. However, the clinical prognostic value of decreased E-cadherin expression in patients with non-small cell lung cancer (NSCLC) remains unsettled. A...
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Article
Ovarian interstitial blood flow changes assessed by transvaginal colour Doppler sonography: predicting ovarian endometrioid cyst-induced injury to ovarian interstitial vessels
To evaluate the blood flow changes and their relationships to microvessel density (MVD) and thrombospondin-1 (TSP-1) by transvaginal colour Doppler sonography (TV-CDS) in the ovarian interstitium to predict ov...
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Article
Simultaneous Determination of Deoxynivalenol and Nivalenol in Traditional Chinese Medicine by SPE and LC
A liquid chromatography method for simultaneous determination of deoxynivalenol (DON) and nivalenol (NIV) in traditional Chinese medicine (TCM) is described for the first time. Different clean-up columns and e...
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Article
Four butenolides are novel cytotoxic compounds isolated from the marine-derived bacterium,Streptoverticillium luteoverticillatum 11014
Four known butenolides were isolated from the ethyl acetate extracts of the culture broth of the marine-derived bacterium,Streptoverticillum luteoverticillatum, by bioassay-guided fractionation. The structures we...
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Chapter and Conference Paper
Fuzzy Support Vector Machines Based on Spherical Regions
Fuzzy Support Vector Machines (FSVMs) based on spherical regions are proposed in this paper. Firstly, the center of the spherite is determined by all the training data. Secondly, the membership functions are d...
