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Article
Open AccessIn situ rumen degradation characteristics and bacterial colonization of whole cottonseed, cottonseed hull and cottonseed meal with different gossypol content
Regarding whole cottonseed (WCS), cottonseed meal (CSM), and cottonseed hull (CSH), in situ rumen incubation was applied to determine their nutrient and gossypol degradation characteristics and bacterial colon...
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Article
Screening of miRNAs associated with lymph node metastasis in Her-2-positive breast cancer and their relationship with prognosis
The aim of this study was to identify some biomarkers for predicting lymph node metastasis and prognosis of human epidermal growth factor receptor 2 (Her-2)-positive breast cancer (BC). We analyzed correlation...
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Article
Research Progresses in Cancer Stem Cells of Three Common Fertility-Related Female Malignancies
With abilities to renew themselves and lead to heterogeneity of tumors, cancer stem cells (CSCs) are similar to stem cells. As three leading causes of death that endanger women’s health, breast cancer, ovarian...
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Article
Open AccessCharacterization of natural co-cultures of Piromyces with Methanobrevibacter ruminantium from yaks grazing on the Qinghai-Tibetan Plateau: a microbial consortium with high potential in plant biomass degradation
Anaerobic fungi reside in the gut of herbivore and synergize with associated methanogenic archaea to decompose ingested plant biomass. Despite their potential for use in bioconversion industry, only a few natu...
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Article
Open AccessNovel germline mutations and unclassified variants of BRCA1 and BRCA2 genes in Chinese women with familial breast/ovarian cancer
Germline mutations in the BRCA1 and BRCA2 genes greatly increase a woman’s risk of develo** breast and/or ovarian cancer. The prevalence and distribution of such mutations differ across races/ethnicities. Sever...
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Article
Effects of heat stress on serum insulin, adipokines, AMP-activated protein kinase, and heat shock signal molecules in dairy cows
Heat stress affects feed intake, milk production, and endocrine status in dairy cows. The temperature-humidity index (THI) is employed as an index to evaluate the degree of heat stress in dairy cows. However, ...
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Article
Overexpression of ILK1 in breast cancer associates with poor prognosis
Integrin-linked kinase 1 (ILK1), a member of the serine/threonine kinases, has been demonstrated to be associated with numerous biological and pathological processes. However, the role of ILK1 in breast cancer...
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Article
Changes in postmastectomy radiotherapy targets in breast cancer in China between 1999 and 2008: an epidemiological study
To provide evidence that could improve management of breast cancer, we conducted a multi-center retrospective epidemiological study to investigate the status of and changes in postmastectomy radiotherapy (PMRT...
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Article
The impact of cyclin D1 overexpression on the prognosis of ER-positive breast cancers: a meta-analysis
Cyclin D1 (CCND1), a key regulator of cell cycle progression, is overexpressed in many human cancers, including breast cancer. However, the impact of CCND1 overexpression in these cancers remains unclear and c...
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Article
Open AccessBreast cancer stage at diagnosis and area-based socioeconomic status: a multicenter 10-year retrospective clinical epidemiological study in China
Although socioeconomic status (SES) has been focused on as a key determinant of cancer stage at diagosis in western countries, there has been no systemic study on the relationship of SES and breast cancer stag...
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Article
Recursive partitioning analysis classification and graded prognostic assessment for non-small cell lung cancer patients with brain metastasis: A retrospective cohort study
To assess prognostic factors and validate the effectiveness of recursive partitioning analysis (RPA) classes and graded prognostic assessment (GPA) in 290 non-small cell lung cancer (NSCLC) patients with brain...
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Article
Open AccessA Nation-Wide multicenter 10-year (1999-2008) retrospective clinical epidemiological study of female breast cancer in china
According to the very limited cancer registry, incidence and mortality rates for female breast cancer in China are regarded to be increasing especially in the metropolitan areas. Representative data on the bre...
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Article
Unilateral hemilaminectomy for patients with intradural extramedullary tumors
A modified hemilaminectomy was introduced in an attempt to explore the operative techniques and the values of the limited approach to spinal cord tumors. Forty-five consecutive patients with intradural extrame...
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Article
Open AccessOxaliplatin-dacarbazine combination chemotherapy for the treatment of advanced soft tissue sarcoma of the limbs
This study was designed to explore the feasibility, safety, and outcomes of pre-operative oxaliplatin-dacarbazine combination therapy for the treatment of advanced soft tissue sarcoma (STS) of the limb.
