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1,295 Result(s)
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Open AccessAssociation between admission pan-immune-inflammation value and short-term mortality in septic patients: a retrospective cohort study
Pan-Immune-Inflammation Value (PIV) has recently received more attention as a novel indicator of inflammation. We aimed to evaluate the association between PIV and prognosis in septic patients. Data were extra...
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Open AccessEnhancing efficiency of protein language models with minimal wet-lab data through few-shot learning
Accurately modeling the protein fitness landscapes holds great importance for protein engineering. Pre-trained protein language models have achieved state-of-the-art performance in predicting protein fitness w...
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Open AccessPulsed laser induced plasma and thermal effects on molybdenum carbide for dry reforming of methane
Dry reforming of methane (DRM) is a highly endothermic process, with its development hindered by the harsh thermocatalytic conditions required. We propose an innovative DRM approach utilizing a 16 W pulsed las...
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Open AccessFe3O4-doped mesoporous carbon cathode with a plumber’s nightmare structure for high-performance Li-S batteries
Shuttling of lithium polysulfides and slow redox kinetics seriously limit the rate and cycling performance of lithium-sulfur batteries. In this study, Fe3O4-dopped carbon cubosomes with a plumber’s nightmare stru...
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Open AccessConstructing and implementing a performance evaluation indicator set for artificial intelligence decision support systems in pediatric outpatient clinics: an observational study
Artificial intelligence (AI) decision support systems in pediatric healthcare have a complex application background. As an AI decision support system (AI-DSS) can be costly, once applied, it is crucial to focu...
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Open AccessA cocktail nanovaccine targeting key entry glycoproteins elicits high neutralizing antibody levels against EBV infection
Epstein-Barr virus (EBV) infects more than 95% of adults worldwide and is closely associated with various malignancies. Considering the complex life cycle of EBV, develo** vaccines targeting key entry glycop...
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Open AccessRPLP1 restricts HIV-1 transcription by disrupting C/EBPβ binding to the LTR
Long-term non-progressors (LTNPs) of HIV-1 infection may provide important insights into mechanisms involved in viral control and pathogenesis. Here, our results suggest that the ribosomal protein lateral stal...
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An alternative broad-specificity pathway for glycan breakdown in bacteria
The vast majority of glycosidases characterized to date follow one of the variations of the ‘Koshland’ mechanisms1 to hydrolyse glycosidic bonds through substitution reactions. Here we describe a large-scale scre...
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Open AccessKnowledge graph-derived feed efficiency analysis via pig gut microbiota
Feed efficiency (FE) is essential for pig production, has been reported to be partially explained by gut microbiota. Despite an extensive body of research literature to this topic, studies regarding the regula...
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Open AccessInfluence of higher body mass index on postoperative nausea and vomiting in patients following thoracic surgery for lung cancer: a propensity score-matched cohort study
This study aimed to quantify the association between body mass index (BMI) and postoperative nausea and vomiting (PONV) within the initial 48 h following thoracic surgery for lung cancer. We then explored whet...
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Open AccessStrongly coupled magneto-exciton condensates in large-angle twisted double bilayer graphene
Excitons, pairs of electrons and holes, undergo a Bose-Einstein condensation at low temperatures. An important platform to study excitons is double-layer two-dimensional electron gases, with two parallel plane...
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Open AccessA bioinspired surface tension-driven route toward programmed cellular ceramics
The intriguing biomineralization process in nature endows the mineralized biological materials with intricate microarchitected structures in a facile and orderly way, which provides an inspiration for processi...
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Open AccessSolvent engineering for scalable fabrication of perovskite/silicon tandem solar cells in air
Perovskite/silicon tandem solar cells hold great promise for realizing high power conversion efficiency at low cost. However, achieving scalable fabrication of wide-bandgap perovskite (~1.68 eV) in air, withou...
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Open AccessMachine learning-guided realization of full-color high-quantum-yield carbon quantum dots
Carbon quantum dots (CQDs) have versatile applications in luminescence, whereas identifying optimal synthesis conditions has been challenging due to numerous synthesis parameters and multiple desired outcomes,...
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Open AccessHigh-throughput screening unveils nitazoxanide as a potent PRRSV inhibitor by targeting NMRAL1
Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) poses a major threat to the global swine industry, yet effective prevention and control measures remain elusive. This study unveils Nitazoxanide (NTZ...
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Open AccessAuthor Correction: Cancer-associated DDX3X mutations drive stress granule assembly and impair global translation
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Open AccessError-Reduced Digital Elevation Model of the Qinghai-Tibet Plateau using ICESat-2 and Fusion Model
The Qinghai-Tibet Plateau (QTP) holds significance for investigating Earth’s surface processes. However, due to rugged terrain, forest canopy, and snow accumulation, open-access Digital Elevation Models (DEMs)...
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Open AccessSphingosine d18:1 promotes nonalcoholic steatohepatitis by inhibiting macrophage HIF-2α
Non-alcoholic steatohepatitis (NASH) is a severe type of the non-alcoholic fatty liver disease (NAFLD). NASH is a growing global health concern due to its increasing morbidity, lack of well-defined biomarkers ...
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Open AccessResearch on spatial carving method of glutenite reservoir based on opacity voxel imaging
The glutenite reservoir in an exploration area in eastern China is well-developed and holds significant exploration potential as an important oil and gas alternative layer. However, due to the influence of sed...
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Open AccessCo-aggregation with Apolipoprotein E modulates the function of Amyloid-β in Alzheimer’s disease
Which isoforms of apolipoprotein E (apoE) we inherit determine our risk of develo** late-onset Alzheimer’s Disease (AD), but the mechanism underlying this link is poorly understood. In particular, the releva...