65 Result(s)
within
Hong**g Cheng
Science, Humanities and Social Sciences, multidisciplinary
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Article
Construction and characterization of partiallyntrC-deleted mutants inAlcaligenes faecalis
To study the effect ofntrC gene product on the expression and regulation of other important nitrogen-fixing genes inAlcaligenes faecalis, partiallyntrC-deleted mutants ofA. faecalis have been generated. To start ...
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The age of formation of the mirabilite and sand wedges in the Hexi Corridor and their paleoclimatic interpretation
Sand wedges in the Hexi Corridor mainly formed in an alluvial gravel stratum of the late Pleistocene and the radiocarbon ages of the eolian sand infilling wedge prove that they were a product of the last ice a...
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Fossil embryos from the Middle and Late Cambrian period of Hunan, south China
Comparative embryology is integral to uncovering the pattern and process of metazoan phylogeny1, but it relies on the assumption that life histories of living taxa are representative of their antecedents. Fossil ...
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Deep structure at northern margin of Tarim Basin
In this paper, a 2D velocity structure of the crust and the upper mantle of the northern margin of the Tarim Basin (TB) has been obtained by ray tracing and theoretical seismogram calculation under the conditi...
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Article
Mechanical analysis of functionally graded plates based on the input data of metallographic diagrams
A microelement method for scale-span analysis of material microstructure and member macro response has been proposed. Instead of material parameter input for traditional mechanical analysis, the method is base...
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Article
Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling
The stability of the Wnt pathway transcription factor β-catenin is tightly regulated by the multi-subunit destruction complex. Deregulated Wnt pathway activity has been implicated in many cancers, making this ...
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Article
Open AccessHigh lake levels on Alxa Plateau during the Late Quaternary
Field investigations including lake shoreline measurement and 14C chronology have been carried out on the Alxa Plateau to better understand the formation and evolution of the high lake levels in northwest China d...
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An obesity genetic risk score predicts risk of insulin resistance among Chinese children
A great number of body mass index (BMI)/obesity-related loci have been identified by recent genome-wide association studies. The objective of the study is to investigate the associations of 11 obesity-related ...
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Article
Open AccessMesoscopic Interactions and Species Coexistence in Evolutionary Game Dynamics of Cyclic Competitions
Evolutionary dynamical models for cyclic competitions of three species (e.g., rock, paper and scissors, or RPS) provide a paradigm, at the microscopic level of individual interactions, to address many issues i...
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Article
Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution
Deep-genome and single-cell sequencing analyses of patient-derived breast cancer xenografts reveal extensive, dynamic and reproducible changes in intra-tumoral mutational clonal composition on engraftment and ...
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Article
Stk38 protein kinase preferentially inhibits TLR9-activated inflammatory responses by promoting MEKK2 ubiquitination in macrophages
NDR/LATS kinase family is highly conserved from yeast to human. It remains unknown whether the members of this family function in innate immune responses. Here we demonstrate that Stk38 negatively regulates TL...
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Open AccessArsenic profile distribution of the wetland argialbolls in the Sanjiang plain of northeastern China
The wetland Argialbolls pedon was chosen to investigate the effects of pedogenic processes and anthropogenic activities on the vertical distribution of As concentrations. Two wetland Argialboll cores (90 cm lo...
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Childhood obesity affects adult metabolic syndrome and diabetes
We seek to observe the association between childhood obesity by different measures and adult obesity, metabolic syndrome (MetS), and diabetes. Thousand two hundred and nine subjects from “Bei**g Blood Pressur...
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Article
Open AccessRecombinant human endostatin enhances the radioresponse in esophageal squamous cell carcinoma by normalizing tumor vasculature and reducing hypoxia
The aim of this study was to investigate the effect of recombinant human endostatin (rh-Endo) in combination with radiation therapy (RT) on esophageal squamous cell carcinoma (ESCC) and explore the potential m...
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Open AccessFamily history of esophageal cancer increases the risk of esophageal squamous cell carcinoma
A population-based case-control was performed to explore familial aggregation of esophageal squamous cell carcinoma (ESCC). Family history of cancer was assessed by a structured questionnaire and from which 2 ...
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Open AccessZyxin-Siah2–Lats2 axis mediates cooperation between Hippo and TGF-β signalling pathways
The evolutionarily conserved Hippo pathway is a regulator that controls organ size, cell growth and tissue homeostasis. Upstream signals of the Hippo pathway have been widely studied, but how microenvironmenta...
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Article
Open AccessAntibiofilm effect enhanced by modification of 1,2,3-triazole and palladium nanoparticles on polysulfone membranes
Biofouling impedes the performance of membrane bioreactors. In this study, we investigated the antifouling effects of polysulfone membranes that were modified by 1,2,3-triazole and palladium (Pd) nanoparticles...
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Open AccessAbrupt sand-dune accumulation at the northeastern margin of the Tibetan Plateau challenges the wet MIS3a inferred from numerous lake-highstands
Over the Tibetan Plateau and adjacent regions, numerous 14C-based lake records revealed a ubiquitous wet climatic period during 40–25 ka (late MIS 3), which is in contradiction with the global pattern of generall...
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Open AccessCell-based phenotypic screening of mast cell degranulation unveils kinetic perturbations of agents targeting phosphorylation
Mast cells play an essential role in initiating allergic diseases. The activation of mast cells are controlled by a complicated signal network of reversible phosphorylation and finding the key regulators invol...
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Open AccessSynthesis of Vertically Standing MoS2 Triangles on SiC
Layered material MoS2 has been attracting much attention due to its excellent electronical properties and catalytic property. Here we report the synthesis of vertically standing MoS2 triangles on silicon carbon(S...
