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Article
Open AccessEvolution of core archetypal phenotypes in progressive high grade serous ovarian cancer
The evolution of resistance in high-grade serous ovarian cancer (HGSOC) cells following chemotherapy is only partially understood. To understand the selection of factors driving heterogeneity before and throug...
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Article
Open AccessPublisher Correction: Genomic analyses of early responses to radiation in glioblastoma reveal new alterations at transcription, splicing, and translation levels
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Article
Open AccessGenomic analyses of early responses to radiation in glioblastoma reveal new alterations at transcription, splicing, and translation levels
High-dose radiation is the main component of glioblastoma therapy. Unfortunately, radio-resistance is a common problem and a major contributor to tumor relapse. Understanding the molecular mechanisms driving r...
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Article
Open AccessTranscriptome profiling of monocytes from XLA patients revealed the innate immune function dysregulation due to the BTK gene expression deficiency
X-linked agammaglobulinemia (XLA) is a rare genetic disorder, caused by mutations in BTK (Bruton’s Tyrosine Kinase) gene. Deep high-throughput RNA sequencing (RNA-Seq) approach was utilized to explore the possibl...
