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  1. Article

    Open Access

    Trabectedin derails transcription-coupled nucleotide excision repair to induce DNA breaks in highly transcribed genes

    Most genotoxic anticancer agents fail in tumors with intact DNA repair. Therefore, trabectedin, anagent more toxic to cells with active DNA repair, specifically transcription-coupled nucleotide excision repair...

    Kook Son, Vakil Takhaveev, Visesato Mor, Hobin Yu, Emma Dillier… in Nature Communications (2024)

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