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  1. Article

    Open Access

    MicroRNA filters Hox temporal transcription noise to confer boundary formation in the spinal cord

    The initial rostrocaudal patterning of the neural tube leads to differential expression of Hox genes that contribute to the specification of motor neuron (MN) subtype identity. Although several 3′ Hox mRNAs are e...

    Chung-Jung Li, Tian Hong, Ying-Tsen Tung, Ya-** Yen… in Nature Communications (2017)

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    Article

    Trehalose Attenuates the Gait Ataxia and Gliosis of Spinocerebellar Ataxia Type 17 Mice

    Spinocerebellar ataxia type 17 (SCA17) is caused by CAG/CAA repeat expansion on the gene encoding a general transcription factor, TATA-box-binding protein (TBP). The CAG repeat expansion leads to the reduced s...

    Zhi-Zhong Chen, Chien-Ming Wang, Guan-Chiun Lee, Ho-Chiang Hsu… in Neurochemical Research (2015)