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  1. Article

    Open Access

    A novel prediction model of pancreatic fistula after pancreaticoduodenectomy using only preoperative markers

    Since clinically relevant postoperative pancreatic fistula (CR-POPF) can cause intra-abdominal hemorrhage and abscesses, leading to surgery-related deaths after pancreaticoduodenectomy (PD), its preoperative p...

    Hiroto Matsui, Yoshitaro Shindo, Daisaku Yamada, Hiroyuki Ogihara in BMC Surgery (2023)

  2. Article

    Open Access

    Cooperation between artificial intelligence and endoscopists for diagnosing invasion depth of early gastric cancer

    The diagnostic ability of endoscopists to determine invasion depth of early gastric cancer is not favorable. We designed an artificial intelligence (AI) classifier for differentiating intramucosal and submucos...

    Atsushi Goto, Naoto Kubota, Jun Nishikawa, Ryo Ogawa, Koichi Hamabe in Gastric Cancer (2023)

  3. Article

    Open Access

    CD4 and FOXP3 as predictive markers for the recurrence of T3/T4a stage II colorectal cancer: applying a novel discrete Bayes decision rule

    We recently reported the relapse-free survival (RFS) significance of the combination of CD4+ and forkhead box P3+ (FOXP3) T-cell densities identified by immunohistochemistry in patients with stage I, II, and III ...

    Yuki Nakagami, Shoichi Hazama, Nobuaki Suzuki, Shin Yoshida in BMC Cancer (2022)

  4. Article

    Open Access

    New cine magnetic resonance imaging parameters for the differential diagnosis of chronic intestinal pseudo-obstruction

    Chronic intestinal pseudo-obstruction (CIPO) is a severe and refractory intestinal motility disorder whose diagnosis currently relies on subjective imaging assessments. Cine magnetic resonance imaging (MRI) ma...

    Hiroki Sato, Hiroyuki Ogihara, Kazuya Takahashi, Yuzo Kawata in Scientific Reports (2021)

  5. Article

    Open Access

    Distinct epigenetic signatures between adult-onset and late-onset depression

    The heterogeneity of major depressive disorder (MDD) is attributed to the fact that diagnostic criteria (e.g., DSM-5) are only based on clinical symptoms. The discovery of blood biomarkers has the potential to...

    Hirotaka Yamagata, Hiroyuki Ogihara, Koji Matsuo, Shusaku Uchida in Scientific Reports (2021)

  6. No Access

    Article

    Serum LOX-1 is a novel prognostic biomarker of colorectal cancer

    Colorectal cancer is the third most common cancer worldwide. If biomarkers can be identified in liquid biopsy, diagnosis and treatment can be optimized even when cancerous tissues are not available. The purpos...

    Chiyo Nakashima-Nakasuga, Shoichi Hazama in International Journal of Clinical Oncology (2020)

  7. Article

    Open Access

    Objective Assessment of the Utility of Chromoendoscopy with a Support Vector Machine

    The utility of chromoendoscopy for early gastric cancer (GC) was determined by machine learning using data of color differences.

    Ryo Ogawa, Jun Nishikawa, Eizaburo Hideura in Journal of Gastrointestinal Cancer (2019)

  8. No Access

    Article

    An Automated Self-Learning Quantification System to Identify Visible Areas in Capsule Endoscopy Images

    Visibility in capsule endoscopic images is presently evaluated through intermittent analysis of frames selected by a physician. It is thus subjective and not quantitative. A method to automatically quantify th...

    Shinichi Hashimoto, Hiroyuki Ogihara, Masato Suenaga in Journal of Medical Systems (2017)

  9. No Access

    Chapter and Conference Paper

    Comparative Study of Classifiers for Prediction of Recurrence of Liver Cancer Using Binary Patterns

    Liver cancer has a high likelihood of recurrence despite complete surgical resection and is thus known as an intractable cancer. If postoperative recurrence of cancer is correctly predicted for each patient as...

    Hiroyuki Ogihara, Yusuke Fujita, Norio Iizuka in Modern Advances in Applied Intelligence (2014)