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  1. Article

    Open Access

    Combined Efficacy of Systemically Acting Diclofenac Sodium Patch and Alpha-2-Delta Calcium Channel Ligand in Chronic Low Back Pain: Subanalysis of a Phase III Study

    Chronic low back pain often comprises mixed pain types and involves multiple factors. Therefore, we hypothesized that the systemic transdermal formulation of diclofenac sodium (DF systemic patch), which is eff...

    Shigeki Yamaguchi, Takaaki Terahara, Koji Okawa, Hiroshi Inakura in Pain and Therapy (2023)

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  2. Article

    Open Access

    Systemically Acting Diclofenac Sodium Patch for Control of Low Back Pain: A Randomized, Double-Blind, Placebo-Controlled Study in Japan

    Nonsteroidal antiinflammatory drugs (NSAIDs) are commonly used for pain disorders such as low back pain and exist in multiple formulations; however, no systemically acting transdermal formulations are availabl...

    Toshihiko Taguchi, Shigeki Yamaguchi, Takaaki Terahara, Koji Okawa… in Pain and Therapy (2023)

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  3. No Access

    Article

    Suppression of nanosilica particle-induced inflammation by surface modification of the particles

    It has gradually become evident that nanomaterials, which are widely used in cosmetics, foods, and medicinal products, could induce substantial inflammation. However, the roles played by the physical character...

    Tomohiro Morishige, Yasuo Yoshioka, Hiroshi Inakura, Aya Tanabe… in Archives of Toxicology (2012)