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    Article

    Differences in branched-chain amino acid to tyrosine ratio (BTR) among etiologies of chronic liver disease progression compared to healthy adults.

    The branched-chain amino acids (BCAAs) to tyrosine (Tyr) ratio (BTR) test is used to evaluate the progression of chronic liver disease (CLD). However, the differences across sex, age, body mass index (BMI) and...

    Masaaki Mino, Akitoshi Sano, Eiji Kakazu, Hiroko Matsubara in Journal of Gastroenterology (2024)

  2. Article

    Open Access

    Clustering by phenotype and genome-wide association study in autism

    Autism spectrum disorder (ASD) has phenotypically and genetically heterogeneous characteristics. A simulation study demonstrated that attempts to categorize patients with a complex disease into more homogeneou...

    Akira Narita, Masato Nagai, Satoshi Mizuno, Soichi Ogishima in Translational Psychiatry (2020)

  3. Article

    Open Access

    Potential identification of vitamin B6 responsiveness in autism spectrum disorder utilizing phenotype variables and machine learning methods

    We investigated whether machine learning methods could potentially identify a subgroup of persons with autism spectrum disorder (ASD) who show vitamin B6 responsiveness by selected phenotype variables. We anal...

    Taku Obara, Mami Ishikuro, Gen Tamiya, Masao Ueki, Chizuru Yamanaka in Scientific Reports (2018)

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    Article

    Association between bacterial community structures and mortality of fish larvae in intensive rearing systems

    Bacterial community structures were analyzed in water used for rearing fish larvae by fluorescence in situ hybridization. In Experiment 1, red sea bream Pagrus major larvae were reared in two commercial seed prod...

    Gentoku Nakase, Yoshizumi Nakagawa, Shigeru Miyashita, Toshiro Nasu in Fisheries Science (2007)