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    Hepatic Stellate Cells Accelerate the Malignant Behavior of Cholangiocarcinoma Cells

    Although tumor–stromal interaction has been discussed, the role of hepatic stellate (HS) cells against cancer, especially cholangiocarcinoma (CC), has not been clarified. The aim of this study is to investigat...

    Hirohisa Okabe MD, Toru Beppu PhD, Hiromitsu Hayashi PhD in Annals of Surgical Oncology (2011)

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    Article

    Hepatic Stellate Cells May Relate to Progression of Intrahepatic Cholangiocarcinoma

    Although cumulative evidence supports the fact that stromal myofibroblasts promote tumor progression, the influence of myofibroblasts on intrahepatic cholangiocarcinoma (ICC) is unclear. We hypothesized that h...

    Hirohisa Okabe MD, Toru Beppu PhD, Hiromitsu Hayashi PhD in Annals of Surgical Oncology (2009)