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8 Result(s)
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Hellmut G. Augustin
Life Sciences
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Article
Open AccessLung endothelium exploits susceptible tumor cell states to instruct metastatic latency
In metastasis, cancer cells travel around the circulation to colonize distant sites. Due to the rarity of these events, the immediate fates of metastasizing tumor cells (mTCs) are poorly understood while the r...
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Article
Open AccessThe angiopoietin receptor Tie2 is atheroprotective in arterial endothelium
Leukocytes and resident cells in the arterial wall contribute to atherosclerosis, especially at sites of disturbed blood flow. Expression of endothelial Tie1 receptor tyrosine kinase is enhanced at these sites...
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Article
Spheroid-based human endothelial cell microvessel formation in vivo
The study of angiogenic endothelial cells (ECs) has in recent years greatly stimulated multiple fields of vascular biology research. A number of cellular models and numerous complex developmental, manipulatory...
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Article
Control of vascular morphogenesis and homeostasis through the angiopoietin–Tie system
The assembly of a functional vascular system requires coordinated signalling between various growth factors and receptors. The Tie receptors and their angiopoi...
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Article
Spheroid-based engineering of a human vasculature in mice
The complexity of the angiogenic cascade limits cellular approaches to studying angiogenic endothelial cells (ECs). In turn, in vivo assays do not allow the analysis of the distinct cellular behavior of ECs durin...
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Chapter
Endothelial Cell Chemotaxis and Chemokinesis Assays
Endothelial cells form a perfectly quiescent monolayer of cells that lines the inside of all blood vessels.Quiescent endothelial cells do not move and divide only rarely within months to years.Yet, upon angiog...
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Book
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Chapter
Vascular Morphogenesis in the Ovary: Introduction and Overview
Vascular morphogenetic processes in the ovary occur cyclically as well as in association with pregnancy. Folliculogenesis and particularly the growth of the corpus luteum are intimately linked to the growth of...
