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  1. Article

    Open Access

    SOX9 Regulates Cancer Stem-Like Properties and Metastatic Potential of Single-Walled Carbon Nanotube-Exposed Cells

    Engineered nanomaterials hold great promise for the future development of innovative products but their adverse health effects are a major concern. Recent studies have indicated that certain nanomaterials, inc...

    Maria A. Voronkova, Sudjit Luanpitpong, Liying Wang Rojanasakul… in Scientific Reports (2017)

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  2. Article

    Open Access

    Mesothelin promotes epithelial-to-mesenchymal transition and tumorigenicity of human lung cancer and mesothelioma cells

    Lung cancer and pleural mesothelioma are two of the most deadly forms of cancer. The prognosis of lung cancer and mesothelioma is extremely poor due to limited treatment modalities and lack of understanding of...

    **aoqing He, Liying Wang, Heimo Riedel, Kai Wang, Yong Yang… in Molecular Cancer (2017)

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  3. No Access

    Protocol

    Yeast as a Host to Screen for Modulators and Regulatory Regions of Mammalian Protein Kinase C Isoforms

    Expression of various mammalian protein kinase C (PKC) isoforms in yeast including Saccharomyces cerevisiae and Schizosaccharomyces pombe results in phenotypic changes such as substantial increases in the cell do...

    Amadeo M. Parissenti, Heimo Riedel in Protein Kinase C Protocols (2003)

  4. No Access

    Article

    PSM, a mediator of PDGF-BB-, IGF-I-, and insulin-stimulated mitogenesis

    PSM/SH2-B has been described as a cellular partner of the FcεRI receptor, insulin receptor (IR), insulin-like growth factor-I (IGF-I) receptor (IGF-IR), and nerve growth factor receptor (TrkA). A function has ...

    Heimo Riedel, Nasim Yousaf, Yuyuan Zhao, Dai He**, You** Deng, Jian Wang in Oncogene (2000)

  5. No Access

    Article

    A chimaeric receptor allows insulin to stimulate tyrosine kinase activity of epidermal growth factor receptor

    The cell surface receptors for insulin and epidermal growth factor (EGF) appear to share a common evolutionary origin, as suggested by structural similarity of cysteine-rich regions in their extracellular doma...

    Heimo Riedel, Thomas J. Dull, Joseph Schlessinger, Axel Ullrich in Nature (1986)