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Altruism and social rewards
Scheggia et al.1 have established a behavioral paradigm to explore preferences for ‘altruistic’ or ‘selfish’ choice behavior in mice. The results suggest that altruistic behavior develops through reinforcement le...
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Author Correction: A wireless haptic interface for programmable patterns of touch across large areas of the skin
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A wireless haptic interface for programmable patterns of touch across large areas of the skin
Haptic interfaces can be used to add sensations of touch to virtual and augmented reality experiences. Soft, flexible devices that deliver spatiotemporal patterns of touch across the body, potentially with ful...
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Open AccessAuthor Correction: The Ca2+-activated chloride channel anoctamin-2 mediates spike-frequency adaptation and regulates sensory transmission in thalamocortical neurons
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Open AccessNon-invasive optical control of endogenous Ca2+ channels in awake mice
Optogenetic approaches for controlling Ca2+ channels provide powerful means for modulating diverse Ca2+-specific biological events in space and time. However, blue light-responsive photoreceptors are, in principl...
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Open AccessThe rostroventral part of the thalamic reticular nucleus modulates fear extinction
The thalamus has been implicated in fear extinction, yet the role of the thalamic reticular nucleus (TRN) in this process remains unclear. Here, in mice, we show that the rostroventral part of the TRN (TRNrv) ...
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Neural circuits underlying a psychotherapeutic regimen for fear disorders
A psychotherapeutic regimen that uses alternating bilateral sensory stimulation (ABS) has been used to treat post-traumatic stress disorder. However, the neural basis that underlies the long-lasting effect of ...
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Open AccessNoninvasive optical activation of Flp recombinase for genetic manipulation in deep mouse brain regions
Spatiotemporal control of gene expression or labeling is a valuable strategy for identifying functions of genes within complex neural circuits. Here, we develop a highly light-sensitive and efficient photoacti...
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Open AccessStress-induced changes in social dominance are scaled by AMPA-type glutamate receptor phosphorylation in the medial prefrontal cortex
The establishment and maintenance of social dominance are critical for social stability and the survival and health of individual animals. Stress lead to depression and a decrease in the social status of depre...
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Open AccessThe Possible Role of Neurobeachin in Extinction of Contextual Fear Memory
Established fear memory becomes vulnerable to disruption after memory retrieval and extinction; this labile state is critical for inhibiting the return of fear memory. However, the labile state has a very narr...
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Open AccessDeficiency of a brain-specific chemokine-like molecule, SAM3, induces cardinal phenotypes of autism spectrum disorders in mice
Chemokines are small secreted signaling proteins produced by a broad range of cells, including immune cells. Several studies have recently suggested potential roles of chemokines and their receptors in the pat...
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Open AccessMice in social conflict show rule-observance behavior enhancing long-term benefit
Disorderly resolution of conflict is costly, whereas orderly resolution by consent rules enables quick settlement. However, it is unclear whether non-human animals can make and observe rules to resolve conflic...
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Open AccessCorrection to: Anti-inflammatory and immune regulatory effects of acupuncture after craniotomy: study protocol for a parallel-group randomized controlled trial
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Open Access26th Annual Computational Neuroscience Meeting (CNS*2017): Part 3
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Open AccessAnti-inflammatory and immune regulatory effects of acupuncture after craniotomy: study protocol for a parallel-group randomized controlled trial
Despite recent advances in the medical and surgical fields, complications such as infection, pneumonia, or brain swelling may occur after a craniotomy. In some patients, perioperative antibiotic prophylaxis ca...
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Open AccessThe thalamic mGluR1-PLCβ4 pathway is critical in sleep architecture
The transition from wakefulness to a nonrapid eye movement (NREM) sleep state at the onset of sleep involves a transition from low-voltage, high-frequency irregular electroencephalography (EEG) waveforms to la...
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Open AccessThe Ca2+-activated chloride channel anoctamin-2 mediates spike-frequency adaptation and regulates sensory transmission in thalamocortical neurons
Neuronal firing patterns, which are crucial for determining the nature of encoded information, have been widely studied; however, the molecular identity and cellular mechanisms of spike-frequency adaptation ar...
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Open Access25th Annual Computational Neuroscience Meeting: CNS-2016
A1 Functional advantages of cell-type heterogeneity in neural circuits
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The ability to solve elementary logic tasks in mice with the knockout of sodium–calcium exchanger gene 2 (NCX2)
Mice with a knockout of the sodium–calcium exchanger 2 (NCX2) gene were statistically significantly more successful than wild-type controls in the solution of two cognitive tasks, the test for the capacity to ext...
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Open AccessThe role of mediodorsal thalamic nucleus in fear extinction
Understanding the neural mechanism underlying the formation and extinction of fear memory would guide the development of advanced strategies for treatment of post-traumatic stress disorder (PTSD), a generalize...