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Chapter
Prevention of Complications
With the development of spinal endoscopic surgery, cervical decompression and discectomy has become the major endoscopic cervical spine surgery. The lack of clear anatomical landmarks and hindered visualizatio...
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Chapter
A Brief History of Unilateral Biportal Endoscopic Spine Surgery
Unilateral biportal endoscopic (UBE) spine surgery has become a direct and advantageous new surgical approach to spinal pathology. This article describes the history of UBE spine surgery and its major mileston...
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Article
Open AccessEnhanced extraction of skin interstitial fluid using a 3D printed device enabling tilted microneedle penetration
Interstitial fluid (ISF) is a body fluid that fills, surrounds cells and contains various biomarkers, but it has been challenging to extract ISF in a reliable and sufficient amount with high speed. To address ...
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Chapter
Biportal Endoscopic Approach for Lumbar Central Stenosis
Two channels were used in biportal endoscopic approach. Endoscopic portal was used for endoscopy and its trocar, and working portal was used for general surgical instruments. Intraoperative anatomical orientat...
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Chapter
Directional Cell Migration Guide for Improved Tissue Regeneration
The field of tissue regeneration has seen a paradigm shift after one wave of technological innovation after another, which has notably made significant contributions to basic cellular response control and over...
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Article
Open AccessNature-inspired rollable electronics
Inspired by the rolling mechanism of the proboscis of a butterfly, rollable electronics that can be rolled and unrolled to a great extent on demand are developed. Generally, electronic devices that are attache...
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Article
Progress in topographically defined scaffolds for drug delivery system
The conventional drug delivery systems including oral and transdermal delivery have limitations. Oral route of drug delivery shows poor drug stability, solubility in physiological barrier of digestive tract. A...
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Article
Open AccessDifferentiated osteoblasts derived decellularized extracellular matrix to promote osteogenic differentiation
The extracellular matrix (ECM) can directly or indirectly influence on regulation of cell functions such as cell adhesion, migration, proliferation and differentiation. The cell derived ECM (CD-ECM) is a usefu...
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Article
Effect of dual growth factor delivery using poly(lactic-co-glycolic acid) mesh on neovascularization in a mouse skin flap model
Skin flaps have the crucial issue that skin necrosis can occur due to tissue ischemia in the distal parts of flaps. To prevent tissue necrosis, skin flaps need to be supplied with sufficient blood perfusion th...
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Article
Synergistic effects of extracellular matrix rigidity and immobilized vascular endothelial growth factor on vascular tube formation and cell morphology of human umbilical vein endothelial cells
Tube formation by endothelial cells (EC) is a one of the key factors involved in initial revascularization during the tissue regeneration process. Several previous studies suggested that EC tube formation can ...
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Article
Open AccessA Case of Complicated Silicosis with a Complex Clinical Course in a Glass Manufacturing Worker
We reported a case of complicated silicosis that occurred in a glass manufacturing plant worker who had presumably been exposed to low-concentration free silica for almost 20 years. To the best of our knowledg...
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Article
Distribution of lactic acid bacteria in garlic (Allium sativum) and green onion (Allium fistulosum) using SDS-PAGE whole cell protein pattern comparison and 16S rRNA gene sequence analysis
Distributions of lactic acid bacteria (LAB) in garlic and green onion samples as kimchi sub-ingredients were analyzed by comparing the SDS-PAGE whole cell protein patterns and 16S rRNA gene sequence analysis. ...
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Article
Open AccessComparison between heparin-conjugated fibrin and collagen sponge as bone morphogenetic protein-2 carriers for bone regeneration
Bone morphogenetic protein-2 (BMP-2) is used to promote bone regeneration. However, the bone regeneration ability of BMP-2 relies heavily on the delivery vehicle. Previously, we have developed heparin-conjugat...
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Article
Open AccessEnhanced skin wound healing by a sustained release of growth factors contained in platelet-rich plasma
Platelet-rich plasma (PRP) contains growth factors that promote tissue regeneration. Previously, we showed that heparin-conjugated fibrin (HCF) exerts the sustained release of growth factors with affinity for ...
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Article
Chemoport with a non-collapsible chamber as a replacement for an Ommaya reservoir in the treatment of leptomeningeal carcinomatosis
The Ommaya reservoir for intraventricular chemotherapy of leptomeningeal carcinomatosis (LMC) patients has been reported to have some complications. We introduced a Chemoport reservoir, with a solid non-collap...
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Article
Skin regeneration with fibroblast growth factor 2 released from heparin-conjugated fibrin
Fibroblast growth factor 2 (FGF2) stimulates skin wound healing but does long-term delivery of FGF2 enhance skin regeneration compared to short-term delivery? Heparin-conjugated fibrin (HCF) was used as a vehi...
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Article
Spinner-flask culture induces redifferentiation of de-differentiated chondrocytes
Implantation of chondrocytes isolated from patients and expanded in number in vitro is being used to treat patients with cartilage injuries. However, chondrocytes de-differentiate during culture with several p...
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Article
The efficacy of acrylic acid grafting and arginine–glycine–aspartic acid peptide immobilization on fibrovascular ingrowth into porous polyethylene implants in rabbits
To determine the effects of acrylic acid (AA) grafting by argon plasma treatment and of immobilization of arginine–glycine–aspartic acid (RGD) peptides on fibrovascular ingrowth rate into high-density porous p...
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Article
Surface modification and fibrovascular ingrowth of porous polyethylene anophthalmic implants
The purpose of this study was to determine the effect of surface modification on the fibrovascular ingrowth into porous polyethylene (PE) spheres (Medpor®), which are used as an anophthalmic socket implant mat...
