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Article
Open AccessThe regional diversity of gut microbiome along the GI tract of male C57BL/6 mice
The proliferation and survival of microbial organisms including intestinal microbes are determined by their surrounding environments. Contrary to popular myth, the nutritional and chemical compositions, water ...
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Article
Open AccessThe function of bacterial HtrA is evolutionally conserved in mammalian HtrA2/Omi
Although the malfunction of HtrA2/Omi leads to Parkinson’s disease (PD), the underlying mechanism has remained unknown. Here, we showed that HtrA2/Omi specifically removed oligomeric α-Syn but not monomeric α-...
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Article
Prognostic significance of the Cdk5 gene in breast cancer: an in silico study
Cyclin-dependent kinase 5 (Cdk5) functions as a tumor promoter in various types of cancer. Cdk5 is overexpressed in breast cancer patients. The prognostic significance of the Cdk5 gene and its expression in br...
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Article
Open AccessIron-dextran as a thermosensitizer in radiofrequency hyperthermia for cancer treatment
Radiofrequency hyperthermia is a recently rediscovered oncotherapy rising in popularity. However, lack of a proper thermosensitizer limits current radiofrequency hyperthermia to be only slightly effective, mos...
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Article
Open AccessTransferrin as a thermosensitizer in radiofrequency hyperthermia for cancer treatment
One of the main characteristics of cancer tissues is poor development of neovascularization that results in a limited blood circulation. Because of this phenomenon, it is harder for cancer tissues to diffuse t...
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Article
Open AccessElucidation of the anti-hyperammonemic mechanism of Lactobacillus amylovorus JBD401 by comparative genomic analysis
Recent experimental evidence showed that lactobacilli could be used as potential therapeutic agents for hyperammonemia. However, lack of understanding on how lactobacilli reduce blood ammonia levels limits app...
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Article
Ultra-High Efficient Colony PCR for High Throughput Screening of Bacterial Genes
Current colony PCR methods are not suitable for screening genes encoded in genomic DNA and are limited to E. coli host strains. Here, we describe an ultra-high efficient colony PCR method for high throughput scre...
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Article
Open AccessGene expression profiles and physiological data from mice fed resveratrol-enriched rice DJ526
The molecular mechanism underlying lifespan extension by resveratrol remains widely discussed. To help study this mechanism, we previously created resveratrol-enriched rice, DJ526, by transferring the resverat...
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Article
Biocompatible and photoluminescent keratin/poly(vinyl alcohol)/carbon quantum dot nanofiber: A novel multipurpose electrospun mat
Carbon quantum dots (C-dots) triggered photoluminescent keratin/poly(vinyl alcohol) (PVA)/C-dots nanofibers (NFs) with optical transparency and biocompatibility were prepared by an electrospinning process. The...
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Article
Open AccessThe resveratrol-enriched rice DJ526 boosts motor coordination and physical strength
The main objective of current genetic modifications in crops is to boost agricultural production or to develop GM crops with an improved nutrient profile by introducing a new trait to the plants. A GM crop sur...
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Article
Open AccessTreatment of obesity with the resveratrol-enriched rice DJ-526
Obesity is the most prevalent disease in the world which poses a serious risk for various chronic diseases. However, currently there are not any therapeutic agents that reduce body weight without causing serio...
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Article
Assessment of the core cryparin promoter from Cryphonectria parasitica for heterologous expression in filamentous fungi
Cryparin is an abundant cell-wall-associated hydrophobin of Cryphonectria parasitica. Although cryparin is encoded as a single copy gene, it is the most abundant protein produced by this fungus when grown in liqu...
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Article
Surface displayed expression of a neutralizing epitope of spike protein from a Korean strain of porcine epidemic diarrhea virus
The neutralizing epitope (K-COE) of the spike protein from a Korean strain of porcine epidemic diarrhea virus (PEDV) has been shown to prevent and foster an immune response to PED, when orally adjusted. The ce...
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Article
Cultural characteristics and extraction of the fungal pigment phleichrome from the phytopathogenic fungusCladosporium phlei
The cultural characteristics of the fungusCladosporium phlei were assessed in order to develop an improved method for the production of the fungal pigment, phleichrome, which is an intermediate in the production ...
