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    Inhibition of Nav1.7 channel by a novel blocker QLS-81 for alleviation of neuropathic pain

    Voltage-gated sodium channel Nav1.7 robustly expressed in peripheral nociceptive neurons has been considered as a therapeutic target for chronic pain, but there is no selective Nav1.7 inhibitor available for t...

    He-ling Niu, Ya-ni Liu, Deng-qi Xue, Li-ying Dong… in Acta Pharmacologica Sinica (2021)