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    Article

    Chronic inflammation with Helicobacter pylori infection is implicated in CD44 overexpression through miR-328 suppression in the gastric mucosa

    Infection with Helicobacter pylori is the main risk factor for development of gastric cancer. CD44 overexpression, especially that of variant 9 (CD44v9), has also been implicated in the local inflammatory respons...

    Takatsugu Ishimoto, Daisuke Izumi, Masayuki Watanabe in Journal of Gastroenterology (2015)

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    Hepatic Stellate Cells Accelerate the Malignant Behavior of Cholangiocarcinoma Cells

    Although tumor–stromal interaction has been discussed, the role of hepatic stellate (HS) cells against cancer, especially cholangiocarcinoma (CC), has not been clarified. The aim of this study is to investigat...

    Hirohisa Okabe MD, Toru Beppu PhD, Hiromitsu Hayashi PhD in Annals of Surgical Oncology (2011)

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    Intrahepatic dissemination of hepatocellular carcinoma after local ablation therapy

    We aimed to clarify the histological features of and risk factors for intrahepatic dissemination after local ablation therapy (LAT) for hepatocellular carcinoma (HCC).

    Toshiro Masuda, Toru Beppu, Takatoshi Ishiko in Journal of Hepato-Biliary-Pancreatic Surge… (2008)