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Article
Open AccessMetabolic remodeling of pyrimidine synthesis pathway and serine synthesis pathway in human glioblastoma
Glioblastoma is the most common brain tumor with dismal outcomes in adults. Metabolic remodeling is now widely acknowledged as a hallmark of cancer cells, but glioblastoma-specific metabolic pathways remain un...
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Article
Impact of red blood cell distribution width and mean platelet volume in patients with ST-segment elevation myocardial infarction
The complete blood cell count is one of the most frequently ordered laboratory tests, and many parameters, including red blood cell distribution width (RDW) and mean platelet volume (MPV), are available. The p...
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Article
Open AccessmiR-4711-5p regulates cancer stemness and cell cycle progression via KLF5, MDM2 and TFDP1 in colon cancer cells
It is important to establish cancer stem cell (CSC)-targeted therapies to eradicate cancer. As it is a CSC marker, we focused on Kruppel-like factor 5 (KLF5) in this study.
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Article
Open AccessSox2 is associated with cancer stem-like properties in colorectal cancer
Sox2 is known as the undifferentiated cell marker. Recent studies have shown that Sox2 may also be involved in the maintenance of cancer stem cells (CSCs) in skin and bladder cancers. In this study, we aimed t...
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Article
Mouse ES cells maintained in different pluripotency-promoting conditions differ in their neural differentiation propensity
Prior to differentiation, embryonic stem (ES) cells in culture are maintained in a so-called “undifferentiated” state, allowing derivation of multiple downstream cell lineages when induced in a directed manner...
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Article
Correlation between cell morphology and aggrecan gene expression level during differentiation from mesenchymal stem cells to chondrocytes
A morphological parameter of polygonal index was defined as the ratio of cell adhesion area versus the square of the major cell axis, and cells that had an adhesion area larger than 4000 μm2 and a polygonal index...
