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Article
Pathological lymph node involvement at surgery is a significant predictive factor of recurrence in locally advanced breast cancer treated with concomitant epirubicin–docetaxel neoadjuvant chemotherapy: a cohort study
Neoadjuvant chemotherapy (NAC) is the standard therapy for locally advanced breast cancer. Recently, several studies have revealed that clearance of axillary lymph node involvement is an independent factor for...
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Article
p53 expression status is a significant molecular marker in predicting the time to endocrine therapy failure in recurrent breast cancer: a cohort study
Hormone receptor status has been one of the most important factors in predicting the response to endocrine therapy in breast cancer patients. However, half of those patients with estrogen receptor-positive tum...
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Article
Complete absence of bile and pancreatic ducts in a newborn: a new entity of congenital anomaly in hepato-pancreatic development
We examined a newborn who had no bile and pancreatic ducts. Hydrops was evident after 29 weeks of gestation and she died shortly after birth, weighing 1,368 g. One of her siblings had died of hydrops at about ...
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Article
Elevated serum ca15-3 levels correlate with positive estrogen receptor and initial favorable outcome in patients who died from recurrent breast cancer
The clinical usefulness of circulating tumor markers in breast cancer as recurrence indicators during follow-up or monitoring treatment response is still an open question. There are some patients with normal t...
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Article
Higher plasma vascular endothelial growth factor levels correlate with menopause, overexpression of p53, and recurrence of breast cancer
Vascular endothelial growth factor (VEGF) is an important factor involved in angiogenesis. Many studies have reported that the expression of VEGF in breast cancer is an unfavorable prognostic factor. However, ...
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Article
An evaluation of predictive factors involved in clinical or pathological response to primary chemotherapy in advanced breast cancer
The usefulness of primary chemotherapy has been widely recognized and applied to routine clinical practice to improve prognosis by downstaging. Nevertheless, none of many trials has been able to show a positiv...
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Article
An evaluation of DNA polymerase α as a prognostic predictor in early breast cancers smaller than 2 cm
We examined the relationship between proliferative activity determined by DNA polymerase α and clinicopathologic variables in breast cancer patients, and evaluated the usefulness of DNA polymerase α as a progn...
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Article
Macromolecular particles of polyglucose synthesized under histochemical conditions in the endothelial cells of rabbit blood vessels
New polyglucose was synthesized artificially under histochemical conditions from glucose 1-phosphate by phosphorylase and branching glycosyltransferase in the endothelial cells of rabbit blood vessels. In elec...
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Article
Variation of phosphorylase distribution in skeletal muscles
Glycogen phosphorylase, glycogen alpha-4 UDP-glucosyl transferase, glycogen, and some enzymes were histochemically examined in rat skeletal muscles. Phosphorylase activity was abundantly demonstrated not only ...
