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  1. Article

    Open Access

    Identification of peptides from honeybee gut symbionts as potential antimicrobial agents against Melissococcus plutonius

    Eusocial pollinators are crucial elements in global agriculture. The honeybees and bumblebees are associated with a simple yet host-restricted gut community, which protect the hosts against pathogen infections...

    Haoyu Lang, Yuwen Liu, Huijuan Duan, Wenhao Zhang, **aosong Hu in Nature Communications (2023)

  2. Article

    Open Access

    Engineered symbiotic bacteria interfering Nosema redox system inhibit microsporidia parasitism in honeybees

    Nosema ceranae is an intracellular parasite invading the midgut of honeybees, which causes serious nosemosis implicated in honeybee colony losses worldwide. The core gut microbiota is involved in protecting again...

    Haoyu Lang, Hao Wang, Haoqing Wang, Zhaopeng Zhong, **anbing **e in Nature Communications (2023)

  3. Article

    Open Access

    Geographical resistome profiling in the honeybee microbiome reveals resistance gene transfer conferred by mobilizable plasmids

    The spread of antibiotic resistance genes (ARGs) has been of global concern as one of the greatest environmental threats. The gut microbiome of animals has been found to be a large reservoir of ARGs, which is ...

    Huihui Sun, **aohuan Mu, Kexun Zhang, Haoyu Lang, Qinzhi Su, **ngan Li in Microbiome (2022)

  4. Article

    Open Access

    Honey bee genetics shape the strain-level structure of gut microbiota in social transmission

    Honey bee gut microbiota transmitted via social interactions are beneficial to the host health. Although the microbial community is relatively stable, individual variations and high strain-level diversity have...

    Jiaqiang Wu, Haoyu Lang, **aohuan Mu, Zi**g Zhang, Qinzhi Su, **aosong Hu in Microbiome (2021)