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Article
Computation method and control strategy of rotating separation flows in hydraulic machinery
Rotating separation flow (RSF) in hydraulic machinery is characterized by the large flow separations and complex vortical structures induced by the effects of strong rotation, large curvature and multiple wall...
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Article
A modified VLES model for simulation of rotating separation flow in axial flow rotating machinery
The internal flow in an axial flow rotating machinery is affected by the rotating characteristics, often accompanied by a strong rotating separation under small flow conditions. At present, the very large eddy...
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Article
A novel Omega-driven dynamic PANS model
A novel Omega (Ω) -driven dynamic partially-averaged Navier-Stokes (PANS) model is proposed in this paper. The ratio of the modeled-to-total turbulent kinetic energies fk is dynamically adjusted by the rigid vort...
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Article
Simulation of the pharmacokinetics of bisoprolol in healthy adults and patients with impaired renal function using whole-body physiologically based pharmacokinetic modeling
To develop and evaluate a whole-body physiologically based pharmacokinetic (WB-PBPK) model of bisoprolol and to simulate its exposure and disposition in healthy adults and patients with renal function impairment.
