-
Article
Open AccessA single-institution retrospective analysis of intraoperative radiation boost during breast-conservation treatment for breast cancer
As part of a breast-conservation strategy for breast cancer, there are presently no data from randomized controlled studies on the use of intraoperative radiation (IORT) as a tumor bed boost. The effectiveness...
-
Article
Open AccessModulation of radiosensitivity of DU145 prostate carcinoma cells by simvastatin
To investigate antiproliferative effects of simvastatin in combination with ionizing radiation on DU145 prostate cancer cells and its influence on cellular HMG-CoA-reductase levels.
-
Article
Open AccessNodal and osseous oligometastatic prostate cancer: a cohort including the introduction of PSMA-PET/CT-guided stereotactic and hypofractionated radiotherapy with elective nodal therapy
Oligometastatic prostate cancer is heavily investigated, and conventionally fractionated elective nodal treatment appears to increase biochemical relapse-free (bRFS) survival. The novelty of this report is to ...
-
Article
Open AccessCorrection to: Metabolic response after 68 Ga‑PSMA‑PET/CT‑directed IGRT/SBRT for oligometastases prostate cancer
-
Article
Open AccessMetabolic response after 68Ga-PSMA-PET/CT-directed IGRT/SBRT for oligometastases prostate cancer
We used 68Ga PSMA PET/CT in the current investigation to assess the metabolic response and local control of metastasis in patients with oligometastatic prostate cancer receiving SBRT.
-
Article
Open AccessA single-center experience with linear accelerator-based stereotactic radiotherapy for meningiomas: hypofractionation and radiosurgery
Meningioma is a common type of benign tumor that can be managed in several ways, ranging from close observation, surgical resection, and various types of radiation. We present here results from a 10 year exper...
-
Article
Open AccessLinac-based stereotactic radiosurgery for brain arteriovenous malformations
Linac stereotactic radiosurgery (SRS) is gaining popularity as a form of radiation treatment for cerebral arteriovenous malformations (AVMs) since the theory of combined radiosurgical and endovascular treatmen...
-
Article
Open AccessFunctional and mutational analysis after radiation and cetuximab treatment on prostate carcinoma cell line DU145
Epidermal Growth Factor Receptor is often overexpressed in advanced prostate carcinoma. In-vitro-studies in prostate carcinoma cell line DU145 have demonstrated increased sensibility to radiation after cetuxim...
-
Article
GPER functions as a tumor suppressor in triple-negative breast cancer cells
The orphan, membrane-bound estrogen receptor (GPER) is expressed at high levels in a large fraction of breast cancer patients and its expression is favorable for patients’ survival.
-
Article
Characterization of the combined cellular survival effects of benzoquinone-ansamycins and ionizing radiation
Benzoquinone-ansamycins were the first compounds characterized with the ability to inhibit the function of heat shock protein 90 and its related family members. We investigated the composite effect of ionizing...
