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Open AccessDiagnose und Therapie der Osteoporose bei Patienten mit chronischer Niereninsuffizienz
Chronische Niereninsuffizienz („chronic kidney disease“ [CKD]): Abnormität der Nierenstruktur oder Nierenfunktion für länger als 3 Monate. Stadienein...
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Article
Open AccessAn experience- and preference-based EQ-5D-3L value set derived using 18 months of longitudinal data in patients who sustained a fracture: results from the ICUROS
EQ-5D-3L preference-based value sets are predominately based on hypothetical health states and derived in cross-sectional settings. Therefore, we derived an experience-based value set from a prospective observ...
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Article
Open AccessUsefulness of the trabecular bone score in maintenance dialysis patients
The number of dialysis patients is steadily increasing. Associated comorbidities include impaired bone and mineral metabolism, termed chronic kidney disease-mineral and bone disorder (CKD-MBD), leading to a hi...
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Article
Open AccessThirty years of hip fracture incidence in Austria: is the worst over?
Nationwide hip fracture incidence in the Austrian population was assessed over a period of 30 years (1989–2018), including 20 years data from a previous study and a recent 10 years follow-up. While absolute nu...
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Article
Inter-observer agreement of vertebral fracture assessment with dual-energy x-ray absorptiometry equipment
To investigate the time and effort needed to perform vertebral morphometry, as well as inter-observer agreement for identification of vertebral fractures on vertebral fracture assessment (VFA) images.
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Article
Open AccessOsteoporose bei pneumologischen Erkrankungen
Asthma und COPD sind die häufigsten obstruktiven Atemwegserkrankungen. Die chronische Inflammation bedingt eine Induktion von proinflammatorischen Zytokinkaskaden. Neben der systemischen Inflammation tragen Hy...
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Article
Open AccessRadiofrequency echographic multi-spectrometry for the in-vivo assessment of bone strength: state of the art—outcomes of an expert consensus meeting organized by the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO)
The purpose of this paper was to review the available approaches for bone strength assessment, osteoporosis diagnosis and fracture risk prediction, and to provide insights into radiofrequency echographic multi...
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Article
Open AccessAssessing the effects of long-term osteoporosis treatment by using conventional spine radiographs: results from a pilot study in a sub-cohort of a large randomized controlled trial
To evaluate the clinical applicability of a software tool developed to extract bone textural information from conventional lumbar spine radiographs, and to test it in a subset of postmenopausal women treated f...
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Article
Quality of life after hip, vertebral, and distal forearm fragility fractures measured using the EQ-5D-3L, EQ-VAS, and time-trade-off: results from the ICUROS
The International Costs and Utilities Related to Osteoporotic fractures Study is a multinational observational study set up to describe the costs and quality of life (QoL) consequences of fragility fracture. T...
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Bone - a casualty of ICU survival?
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Mortality After Hip Fracture in Austria 2008–2011
Osteoporosis-related hip fractures represent a substantial cause of mortality and morbidity in industrialized countries like Austria. Identification of groups at high risk for mortality after hip fracture is c...
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Article
Femoral geometric parameters and BMD measurements by DXA in adult patients with different types of osteogenesis imperfecta
Osteogenesis imperfecta (OI) is an inherited disorder characterized by increased bone fragility with recurrent fractures that leads to skeletal deformities in severe cases. Consequently, in most OI patients, t...
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Open AccessEconomic burden of osteoporotic fractures in Austria
Osteoporotic fractures impose a huge economic burden on society. Though several cost of illness studies from other countries exist, no equivalent study has been conducted in Austria. Our study aims at assessin...
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Österreichischer Leitfaden zur medikamentösen Therapie der postmenopausalen Osteoporose: Addendum 2010
The Austrian Society for Bone and Mineral Research routinely publishes evidence-based guidelines for the treatment of postmenopausal osteoporosis. The fully human monoclonal antibody denosumab (Prolia®) has been ...
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Article
Diagnostik der Osteoporose
The diagnostic approach to osteoporosis usually involves an ample risk assessment, a physical examination, a radiograph of the thoracic and lumbar spine, a bone densitometry using dual X-ray absorptiometry, an...
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Österreichischer Leitfaden zur medikamentösen Therapie der postmenopausalen Osteoporose – Update 2009
Osteoporosis is a systemic skeletal disease characterized by diminished bone mass and deterioration of bone microarchitecture, leading to increased fragility and subsequent increased fracture risk. Therapeutic...
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Article
Strontium ranelate: a novel concept for the treatment of osteoporosis
The di-strontium salt strontium ranelate, a novel orally active agent consisting of two atoms of stable strontium and the organic moiety ranelic acid, has been developed for the treatment of osteoporosis. It h...
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Article
The effects of chronic hypobaric conditions
Many studies have concentrated on investigating the effects of short- and medium-term hypobaric conditions in people living at low altitudes. In contrast, only little is known about long-term or genetic adapta...
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Article
Hypovitaminosis D, impaired bone turnover and low bone mass are common in patients with peripheral arterial disease
Hypovitaminosis D is common in patients with peripheral arterial disease (PAD). Subsequent secondary hyperparathyroidism and osteomalacia contribute to bone pain and myalgias, and so aggravate clinical symptom...
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Article
Reconstructed mass-spectrometric pattern for characterization of carbon compounds in smoker’s lung in situ
Cigarette smoke is a major anthropogenic pollutant and contributes to the permanent load of ambient particulate matter in the air, particularly indoors. It is the leading risk factor for premature loss of life...