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    Article

    A KLF2-BMPER-Smad1/5 checkpoint regulates high fluid shear stress-mediated artery remodeling

    Vascular remodeling to match arterial diameter to tissue requirements commonly fails in ischemic disease. Endothelial cells sense fluid shear stress (FSS) from blood flow to maintain FSS within a narrow range ...

    Hanqiang Deng, Jiasheng Zhang, Yewei Wang, Divyesh Joshi in Nature Cardiovascular Research (2024)

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    Open Access

    Structure and vascular function of MEKK3–cerebral cavernous malformations 2 complex

    Cerebral cavernous malformations 2 (CCM2) loss is associated with the familial form of CCM disease. The protein kinase MEKK3 (MAP3K3) is essential for embryonic angiogenesis in mice and interacts physically wi...

    Oriana S. Fisher, Hanqiang Deng, Dou Liu, Ya Zhang, Rong Wei in Nature Communications (2015)