5 Result(s)
within
Hanna Lee
Biomedicine
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Article
Open AccessSerum IGF-1 in patients with rheumatoid arthritis: correlation with disease activity
Insulin-like growth factor (IGF)-1 participates in modulating immunity and inflammation. Its bioactivity is controlled by six IGF-binding proteins (IGFBP-1 to IGFBP-6). In particular, the IGFBP-3 level is repo...
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Article
Open AccessEstablishment and characterization of patient-derived xenografts as paraclinical models for head and neck cancer
We investigated whether head and neck squamous cell carcinoma (HNSCC) patient-derived xenografts (PDXs) reaffirm patient responses to anti-cancer therapeutics.
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Article
Microtubule-driven spatial arrangement of mitochondria promotes activation of the NLRP3 inflammasome
Much is known about the activation of the NLRP3 inflammasome; however, the control of its physical assembly is less well understood. Akira and colleagues demonstrate that acetylated tubulin drives assembly of ...
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Article
Common variation at 6q16 within HACE1 and LIN28B influences susceptibility to neuroblastoma
John Maris and colleagues identify common variants at 6q16 associated with neuroblastoma susceptibility. The risk variants are located near the HACE1 and LIN28B genes, both of which show altered expression in adv...
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Article
In vivo tumor targeting imaging of cyclic RGD-modified heparin derivative to αvβ3-integrin expressing tumor
Therapeutic target for over-expressed αvβ3 integrins in angiogenic endothelial cells and tumors is one of the promising approaches for cancer imaging and therapy. In the previous study, we demonstrated that hepar...
