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Protocol
Cloning Strategies for the Generation of Recombinant Capripoxvirus Through the Use of Screening and Selection Markers
The ability to manipulate through gene knockouts and gene insertions has become an increasingly valuable research tool in elucidating the function of individual genes of , as well as in the development of c...
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Article
Open AccessA novel Schmallenberg virus subunit vaccine candidate protects IFNAR-/- mice against virulent SBV challenge
Schmallenberg virus (SBV), an arthropod-transmitted pathogenic bunyavirus, continues to be a threat to the European livestock industry, causing morbidity and mortality among young ruminant livestock. Here, we ...
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Protocol
Generation of Recombinant Capripoxvirus Vectors for Vaccines and Gene Knockout Function Studies
The ability to manipulate capripoxvirus through gene knockouts and gene insertions has become an increasingly valuable research tool in elucidating the function of individual genes of capripoxvirus, as well as...
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Article
B lymphocytes from early vertebrates have potent phagocytic and microbicidal abilities
The present paradigm dictates that phagocytosis is accomplished mainly by 'professional' phagocytes (such as macrophages and monocytes), whereas B cells lack phagocytic capabilities. Here we demonstrate that B...
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Article
Maternal transfer of complement components C3-1, C3-3, C3-4, C4, C5, C7, Bf, and Df to offspring in rainbow trout (Oncorhynchus mykiss)
Defense mechanisms in develo** fish are poorly known but before maturation of lymphoid organs and immunocompetence, innate mechanisms are essential. The complement system represents a major part of innate im...
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Article
Evolution of complement as an effector system in innate and adaptive immunity
For a long time, the complement system in mammals has been regarded as a biological system that plays an essential role in innate immunity. More recently, it has been recognized that the complement system cont...
