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  1. Article

    Open Access

    Modeling acute myocardial infarction and cardiac fibrosis using human induced pluripotent stem cell-derived multi-cellular heart organoids

    Heart disease involves irreversible myocardial injury that leads to high morbidity and mortality rates. Numerous cell-based cardiac in vitro models have been proposed as complementary approaches to non-clinica...

    Myeong** Song, Da Bin Choi, Jeong Suk Im, Ye Na Song, Ji Hyun Kim in Cell Death & Disease (2024)

  2. No Access

    Chapter and Conference Paper

    Hand-in-O: Exploring Possibilities of Sensing and Constraining the Gestures with its Frame to Provide Light and Sound Feedback

    The invisibility of a physical outline to constrain users within an area for conducting their gesture commands frequently results in making errors, which may further affect the less use of the gesture inputs. ...

    Hanbyeol Lee, Beom Kim, Seungkyu Gim in [ ] With Design: Reinventing Design Modes (2022)

  3. No Access

    Article

    CMIT/MIT induce apoptosis and inflammation in alveolar epithelial cells through p38/JNK/ERK1/2 signaling pathway

    The 5-chloro-2-methyl-2h-isothiazolin-3-one and 2-methyl-2h-isothiazol-3-one (CMIT/MIT) are widespread biocides that commonly found in variety of water-soluble consumer products including dentifrice, germicide...

    Jooyeon Lee, Hanbyeol Lee, Soo** Jang, Seok-Ho Hong in Molecular & Cellular Toxicology (2019)

  4. No Access

    Article

    l-carnosine induces apoptosis/cell cycle arrest via suppression of NF-κB/STAT1 pathway in HCT116 colorectal cancer cells

    l-carnosine, a dipeptide of the amino acids β-alanine and histidine, is found in various tissues, such as the central nervous system and skeletal muscles. Recently, l-carnosine has been reported to possess anti-t...

    Jooyeon Lee, Jeong-Ran Park, Hanbyeol Lee in In Vitro Cellular & Developmental Biology … (2018)

  5. No Access

    Article

    Functional characteristics of mesenchymal stem cells derived from the adipose tissue of a patient with achondroplasia

    Mesenchymal stem cells (MSCs) can be isolated from various tissues including bone marrow, adipose tissue, skin dermis, and umbilical Wharton’s jelly as well as injured tissues. MSCs possess the capacity for se...

    Jeong-Ran Park, Hanbyeol Lee, Chung-Hyo Kim in In Vitro Cellular & Developmental Biology … (2016)

  6. No Access

    Article

    Isolation of human dermis derived mesenchymal stem cells using explants culture method: expansion and phenotypical characterization

    Recent studies have reported that stem cells can be isolated from a wide range of tissues including bone marrow, fatty tissue, adipose tissue and placenta. Moreover, several studies also suggest that skin derm...

    Jeong-Ran Park, Eunjeong Kim, Jungwon Yang, Hanbyeol Lee in Cell and Tissue Banking (2015)

  7. Article

    Nicotine inhibits the proliferation by upregulation of nitric oxide and increased HDAC1 in mouse neural stem cells

    Cigarette smoking (CS) is considered one of the major risk factors to cause neurodegenerative disorders. Nicotine is the main chemical in CS which is responsible for dysfunction of the brain as a neuroteratoge...

    Hanbyeol Lee, Jeong-Ran Park, Jungwon Yang in In Vitro Cellular & Developmental Biology … (2014)